{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,23]],"date-time":"2025-10-23T10:44:39Z","timestamp":1761216279757},"reference-count":24,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2015,9,1]],"date-time":"2015-09-01T00:00:00Z","timestamp":1441065600000},"content-version":"tdm","delay-in-days":5356,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Am. J. Med. Genet."],"published-print":{"date-parts":[[2001,10,1]]},"DOI":"10.1002\/ajmg.1511","type":"journal-article","created":{"date-parts":[[2002,8,25]],"date-time":"2002-08-25T22:31:19Z","timestamp":1030314679000},"page":"133-137","source":"Crossref","is-referenced-by-count":15,"title":["Mutation of thePRNP gene at codon 211 in familial Creutzfeldt-Jakob disease"],"prefix":"10.1002","volume":"103","author":[{"given":"A.","family":"Ladogana","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Almonti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Petraroli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.","family":"Giaccaglini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Ciarmatori","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Q.G.","family":"Li\ufffd","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Bevivino","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F.","family":"Squitieri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Pocchiari","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2001]]},"reference":[{"key":"BIB1","doi-asserted-by":"crossref","first-page":"3280","DOI":"10.1021\/bi982328z","volume":"38","author":"Cappai","year":"1999","journal-title":"Biochemistry"},{"key":"BIB2","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1016\/S0896-6273(00)81105-8","volume":"24","author":"Chesebro","year":"1999","journal-title":"Neuron"},{"key":"BIB3","doi-asserted-by":"crossref","first-page":"1989","DOI":"10.1016\/S0140-6736(05)61335-9","volume":"352","author":"D'Alessandro","year":"1998","journal-title":"Lancet"},{"key":"BIB4","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1007\/BF00143125","volume":"7","author":"Goldfarb","year":"1991","journal-title":"Eur J Epidemiol"},{"key":"BIB5","doi-asserted-by":"crossref","first-page":"806","DOI":"10.1126\/science.1439789","volume":"258","author":"Goldfarb","year":"1992","journal-title":"Science"},{"key":"BIB6","doi-asserted-by":"crossref","first-page":"1994","DOI":"10.1056\/NEJM199812313392707","volume":"339","author":"Johnson","year":"1998","journal-title":"N Engl J Med"},{"key":"BIB7","doi-asserted-by":"crossref","first-page":"6855","DOI":"10.1093\/emboj\/18.23.6855","volume":"18","author":"Manson","year":"1999","journal-title":"EMBO J"},{"key":"BIB8","doi-asserted-by":"crossref","first-page":"27110","DOI":"10.1016\/S0021-9258(19)61486-9","volume":"275","author":"Miravalle","year":"2000","journal-title":"J Biol Chem"},{"key":"BIB9","doi-asserted-by":"crossref","first-page":"10962","DOI":"10.1073\/pnas.90.23.10962","volume":"90","author":"Pan","year":"1993","journal-title":"Proc Natl Acad Sci USA"},{"key":"BIB10","doi-asserted-by":"crossref","first-page":"482","DOI":"10.1002\/(SICI)1098-1004(200005)15:5<482::AID-HUMU16>3.0.CO;2-1","volume":"15","author":"Peoc'h","year":"2000","journal-title":"Online. Hum Mutat"},{"key":"BIB11","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/S0165-0270(00)00216-8","volume":"99","author":"Petraroli","year":"2000","journal-title":"J Neurosci Meth"},{"key":"BIB12","doi-asserted-by":"crossref","first-page":"979","DOI":"10.1097\/00005072-199810000-00010","volume":"57","author":"Piccardo","year":"1998","journal-title":"J Neuropathol Exp Neurol"},{"key":"BIB13","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1016\/0098-2997(94)90042-6","volume":"15","author":"Pocchiari","year":"1994","journal-title":"Molec Aspects Med"},{"key":"BIB14","doi-asserted-by":"crossref","first-page":"802","DOI":"10.1002\/ana.410340608","volume":"34","author":"Pocchiari","year":"1993","journal-title":"Ann Neurol"},{"key":"BIB15","doi-asserted-by":"crossref","first-page":"13363","DOI":"10.1073\/pnas.95.23.13363","volume":"95","author":"Prusiner","year":"1998","journal-title":"Proc Natl Acad Sci USA"},{"key":"BIB16","doi-asserted-by":"crossref","first-page":"11667","DOI":"10.1073\/pnas.95.20.11667","volume":"95","author":"Riek","year":"1998","journal-title":"Proc Natl Acad Sci USA"},{"key":"BIB17","first-page":"9","volume-title":"Molecular cloning: a laboratory manual","author":"Sambrook","year":"1989","unstructured":"1989. Molecular cloning: a laboratory manual. Plainview, NY: Cold Spring Harbor Laboratory Press. p 9.20-9.21."},{"key":"BIB18","doi-asserted-by":"crossref","first-page":"7358","DOI":"10.1073\/pnas.83.19.7358","volume":"83","author":"Sparkes","year":"1986","journal-title":"Proc Nat Acad Sci U S A"},{"key":"BIB19","doi-asserted-by":"crossref","first-page":"31048","DOI":"10.1074\/jbc.273.47.31048","volume":"47","author":"Swietnicki","year":"1998","journal-title":"J Biol Chem"},{"key":"BIB20","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1016\/S0014-5793(99)00428-7","volume":"450","author":"Warwicker","year":"1999","journal-title":"FEBS Lett"},{"key":"BIB21","doi-asserted-by":"crossref","first-page":"763","DOI":"10.1002\/ana.410430611","volume":"43","author":"Will","year":"1998","journal-title":"Ann Neurol"},{"key":"BIB22","author":"World Health Organization","year":"1998","journal-title":"WHO\/EMC\/ZDI\/98.9"},{"key":"BIB23","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1073\/pnas.97.1.145","volume":"97","author":"Zahn","year":"2000","journal-title":"Proc Natl Acad Sci U S A"},{"key":"BIB24","doi-asserted-by":"crossref","first-page":"811","DOI":"10.1212\/WNL.55.6.811","volume":"55","author":"Zerr","year":"2000","journal-title":"Neurology"}],"container-title":["American Journal of Medical Genetics"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fajmg.1511","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full\/10.1002\/ajmg.1511","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,3]],"date-time":"2023-04-03T03:45:29Z","timestamp":1680493529000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ajmg.1511"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2001]]},"references-count":24,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2001,10,1]]}},"URL":"https:\/\/doi.org\/10.1002\/ajmg.1511","relation":{},"ISSN":["0148-7299","1096-8628"],"issn-type":[{"value":"0148-7299","type":"print"},{"value":"1096-8628","type":"electronic"}],"subject":[],"published":{"date-parts":[[2001]]}}}