{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T08:33:44Z","timestamp":1791016424224,"version":"4.1.0"},"reference-count":48,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2002,9,18]],"date-time":"2002-09-18T00:00:00Z","timestamp":1032307200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["American J of Med Genetics Pt A"],"published-print":{"date-parts":[[2003,1,30]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Women recruited from a hereditary cancer registry provided ratings of distress associated with different aspects of high\u2010risk status and genetic testing and completed measures of general psychological distress, emotional and social health, and role functioning. Overall, high\u2010risk status was rated as more distressing than undergoing genetic testing. Women without a personal history of cancer rated the level of distress associated with a positive test result to be greater than that associated with high\u2010risk status. In contrast, level of distress associated with a positive test result was not significantly different from that associated with high\u2010risk status for women with a personal history of cancer. Furthermore, women with a personal cancer history also anticipated that if they had an altered gene associated with increased risk of cancer, it would be less distressing than their diagnosis of cancer had been. Women with the highest ratings of cancer\u2010related stress were less inclined to obtain testing, but were not more generally distressed or maladjusted. The need to interpret psychological distress and the stressfulness of genetic testing among high\u2010risk women with respect to relevant comparison data is discussed. \u00a9 2002 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/ajmg.a.10844","type":"journal-article","created":{"date-parts":[[2002,12,28]],"date-time":"2002-12-28T17:02:21Z","timestamp":1041094941000},"page":"222-228","source":"Crossref","is-referenced-by-count":45,"title":["What do ratings of cancer\u2010specific distress mean among women at high risk of breast and ovarian cancer?"],"prefix":"10.1002","volume":"116A","author":[{"given":"James C.","family":"Coyne","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Linda","family":"Kruus","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Melissa","family":"Racioppo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kathleen A.","family":"Calzone","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katrina","family":"Armstrong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2002,9,18]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02895156"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1037\/0022-006X.70.1.258"},{"key":"e_1_2_5_4_1","doi-asserted-by":"crossref","first-page":"1970","DOI":"10.1001\/jama.1993.03500150082032","article-title":"Genetic counseling for families with inherited susceptibility to breast and ovarian cancer","volume":"269","author":"Biesecker BB","year":"1993","journal-title":"J Am Med Assoc"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00435221"},{"key":"e_1_2_5_6_1","first-page":"254","article-title":"Measurement of the quality of life during different clinical phases of breast cancer","volume":"98","author":"Chie WC","year":"1999","journal-title":"J Formosan Med Assoc"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.1320540303"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-7610.1993.tb01035.x"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1037\/0893-3200.13.4.629"},{"key":"e_1_2_5_10_1","doi-asserted-by":"crossref","first-page":"404","DOI":"10.1037\/0022-3514.61.3.404","article-title":"Couples coping with myocardial infarction: a contextual prospective on wives' distress","volume":"6","author":"Coyne JC","year":"1991","journal-title":"J Personality Soc Psychol"},{"key":"e_1_2_5_11_1","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1037\/0022-006X.55.3.347","article-title":"Living with a depressed person","volume":"55","author":"Coyne JC","year":"1987","journal-title":"J Consult Clin Psychol"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1037\/0022-006X.68.5.864"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0962-1849(00)80009-8"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1097\/00006842-199801000-00074"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1037\/0278-6133.16.1.63"},{"key":"e_1_2_5_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/1097-4679(197710)33:4<981::AID-JCLP2270330412>3.0.CO;2-0"},{"key":"e_1_2_5_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/bs.3830190102"},{"key":"e_1_2_5_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1096-8628(19970711)71:1<63::AID-AJMG12>3.0.CO;2-T"},{"key":"e_1_2_5_19_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2214.1999.00116.x"},{"key":"e_1_2_5_20_1","doi-asserted-by":"publisher","DOI":"10.1037\/0022-006X.62.3.550"},{"key":"e_1_2_5_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0447.1995.tb09605.x"},{"key":"e_1_2_5_22_1","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/87.18.1372"},{"key":"e_1_2_5_23_1","first-page":"1694","article-title":"Health status in systemic lupus erythematosus compared to rheumatoid arthritis and healthy controls","volume":"26","author":"Gilboe IM","year":"1999","journal-title":"J Rheumatol"},{"key":"e_1_2_5_24_1","first-page":"45","article-title":"Assessment of psychiatric illness severisty by family physicians","volume":"12","author":"Hesbacher P","year":"1978","journal-title":"Soc Sci Med"},{"key":"e_1_2_5_25_1","first-page":"6","article-title":"Psychiatric illness in family practice","volume":"41","author":"Hesbacher PT","year":"1980","journal-title":"J Clin Psychiatry"},{"key":"e_1_2_5_26_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.psy.42.2.100"},{"key":"e_1_2_5_27_1","unstructured":"HoughRL LandsrerkJA StoneJD JacobsonGR.1982.Comparison of psychiatric screening questionnaires for primary care patients: final report for NIMH contract 278\u20100036."},{"key":"e_1_2_5_28_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.306.6890.1437"},{"key":"e_1_2_5_29_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005650-199205001-00024"},{"key":"e_1_2_5_30_1","first-page":"199","article-title":"Knowledge, attitudes, and interest in genetic testing among 1,000 women at risk for developing breast cancer","volume":"38","author":"Kash KM","year":"1997","journal-title":"Psychosomatics"},{"key":"e_1_2_5_31_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.1994.12.4.843"},{"key":"e_1_2_5_32_1","first-page":"172","article-title":"Young women at increased risk for breast cancer: perceived risk, psychological well\u2010being, and surveillance behavior","volume":"16","author":"Lerman C","year":"1994","journal-title":"Monographs Natl Cancer Inst"},{"key":"e_1_2_5_33_1","doi-asserted-by":"crossref","first-page":"1885","DOI":"10.1001\/jama.1996.03530480027036","article-title":"BRCA1 testing in families with hereditary breast\u2010ovarian cancer: a prospective study of patient decision making and outcomes","volume":"275","author":"Lerman C","year":"1996","journal-title":"J Am Med Assoc"},{"key":"e_1_2_5_34_1","doi-asserted-by":"publisher","DOI":"10.1037\/0022-006X.65.3.414"},{"key":"e_1_2_5_35_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.1998.16.5.1650"},{"key":"e_1_2_5_36_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005650-199807000-00007"},{"key":"e_1_2_5_37_1","doi-asserted-by":"publisher","DOI":"10.1002\/1096-8628(20010101)98:1<15::AID-AJMG1014>3.0.CO;2-0"},{"key":"e_1_2_5_38_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0142(19970601)79:11<2219::AID-CNCR21>3.0.CO;2-Y"},{"key":"e_1_2_5_39_1","doi-asserted-by":"publisher","DOI":"10.1023\/A:1018748712987"},{"key":"e_1_2_5_40_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005650-199303000-00006"},{"key":"e_1_2_5_41_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.7545954"},{"key":"e_1_2_5_42_1","doi-asserted-by":"publisher","DOI":"10.1037\/0022-006X.69.2.339"},{"key":"e_1_2_5_43_1","doi-asserted-by":"publisher","DOI":"10.1177\/014662167700100306"},{"key":"e_1_2_5_44_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0090-4295(99)00203-4"},{"key":"e_1_2_5_45_1","doi-asserted-by":"publisher","DOI":"10.1038\/ng0396-333"},{"key":"e_1_2_5_46_1","doi-asserted-by":"publisher","DOI":"10.1002\/pon.510"},{"key":"e_1_2_5_47_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005650-199206000-00002"},{"key":"e_1_2_5_48_1","first-page":"312","article-title":"The functional status of inner\u2010city primary care patients: diminished function in a family practice population and its potential determinants","volume":"47","author":"Woolf SH","year":"1998","journal-title":"J Family Pract"},{"key":"e_1_2_5_49_1","doi-asserted-by":"publisher","DOI":"10.1038\/378789a0"}],"container-title":["American Journal of Medical Genetics Part A"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fajmg.a.10844","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ajmg.a.10844","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,18]],"date-time":"2023-11-18T01:43:56Z","timestamp":1700271836000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ajmg.a.10844"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2002,9,18]]},"references-count":48,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2003,1,30]]}},"alternative-id":["10.1002\/ajmg.a.10844"],"URL":"https:\/\/doi.org\/10.1002\/ajmg.a.10844","archive":["Portico"],"relation":{},"ISSN":["1552-4825","1552-4833"],"issn-type":[{"value":"1552-4825","type":"print"},{"value":"1552-4833","type":"electronic"}],"subject":[],"published":{"date-parts":[[2002,9,18]]}}}