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It provides background on CHARGE syndrome, diagnostic criteria, and the relationship of sensory and other physical deficits with both development and behavior. Four themes related to our developing understanding of behavior in CHARGE are described: children with CHARGE have behaviors different from those seen in other syndromes with or without deafblindness. The behavior they display is often very adaptive to their environment and to their own disabilities. These behaviors may be partially related to problems with arousal and self\u2010regulation. And, finally, all papers point to behavior as communication, especially within relationships, where it is essential for maximizing intellectual and social outcomes. \u00a9 2005 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/ajmg.a.30541","type":"journal-article","created":{"date-parts":[[2005,1,6]],"date-time":"2005-01-06T19:18:47Z","timestamp":1105039127000},"page":"228-231","source":"Crossref","is-referenced-by-count":35,"title":["Behavior in CHARGE syndrome: Introduction to the special topic"],"prefix":"10.1002","volume":"133A","author":[{"given":"Timothy S.","family":"Hartshorne","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Margaret A.","family":"Hefner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandra 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