{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T01:58:59Z","timestamp":1789955939600,"version":"4.0.1"},"reference-count":18,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2005,1,7]],"date-time":"2005-01-07T00:00:00Z","timestamp":1105056000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["American J of Med Genetics Pt A"],"published-print":{"date-parts":[[2005,3,15]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The \u201cR\u201d in the mnemonic \u201cCHARGE\u201d has historically stood for \u201cRetardation of Growth and Development.\u201d Early medical reports describing mental retardation in CHARGE syndrome have not used convincing means to assess this attribute. This article investigated the range of developmental ability in individuals with CHARGE as measured through an adaptive behavior scale, the Adaptive Behavior Evaluation Scale (ABES) [Carney (<jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"#bib6\">1995<\/jats:ext-link>): The Adaptive Behavior Evaluation Scale home version technical manual\u2010revised. 126p.], over time. Parents of individuals with CHARGE syndrome were surveyed twice over a 4\u2010year time span (N\u2009=\u2009100, 85) to obtain information about adaptive behavior and specific CHARGE characteristics. There was a significant decline in ABES scores over the 4\u2010year period. However, at Time two, one\u2010half of the children achieved a standard score above 70. Correlation and regression analyses at Time one and Time two revealed negative relationships between (a) age at walking, (b) degree of hearing impairment, (c) degree of visual impairment, and (d) medical involvement variables and the dependent variable, adaptive behavior. In both studies, age at walking was the best predictor of scores. Analysis of variance confirmed that medical involvement and degree of vision impairment were related to adaptive behavior scores because they were also related to age at walking. Age at walking and medical involvement at Time one were found to be significantly different between those who improved and declined in adaptive behavior scores over time. Adaptive behavior scores from both studies revealed a much broader and higher\u2010reaching range of ability for this population than has been previously reported in the literature. \u00a9 2005 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/ajmg.a.30546","type":"journal-article","created":{"date-parts":[[2005,1,7]],"date-time":"2005-01-07T23:29:10Z","timestamp":1105140550000},"page":"262-267","source":"Crossref","is-referenced-by-count":36,"title":["Adaptive behavior in children with CHARGE syndrome"],"prefix":"10.1002","volume":"133A","author":[{"given":"Nancy","family":"Salem\u2010Hartshorne","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susan","family":"Jacob","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2005,1,7]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2214.1993.tb00744.x"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1136\/adc.65.2.217"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1177\/000992289803700302"},{"key":"e_1_2_7_5_1","volume-title":"Psychology 767 test reviews and class materials","author":"Bradley\u2010Johnson S","year":"1997"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.a.30547"},{"key":"e_1_2_7_7_1","first-page":"126p","volume-title":"The Adaptive Behavior Evaluation Scale home version technical manual\u2010revised","author":"Carney SB","year":"1995"},{"key":"e_1_2_7_8_1","first-page":"1","volume-title":"CHARGE syndrome: A management manual for parents","author":"Davenport SLH","year":"1999"},{"key":"e_1_2_7_9_1","first-page":"480p","volume-title":"Mail and internet surveys: The tailored design method","author":"Dillman D","year":"1999"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(79)80513-2"},{"key":"e_1_2_7_11_1","first-page":"41","article-title":"Challenging behavior in CHARGE syndrome","volume":"7","author":"Hartshorne TS","year":"2004","journal-title":"Ment Health Asp Dev Disab"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.1320390112"},{"key":"e_1_2_7_13_1","unstructured":"MarH.1998.Psychological evaluation of children who are deaf\u2010blind: An overview with recommendations for practice. [Electronic database.] Monmouth. D\u2010B Link: The National Information Clearinghouse on Children Who Are Deaf\u2010Blind [Producer and Distributor]."},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1136\/jmg.25.3.147"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(81)80454-4"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1177\/105381510402600405"},{"key":"e_1_2_7_17_1","first-page":"620p","volume-title":"Assessment of children: Behavioral and clinical applications","author":"Sattler JM","year":"2002"},{"key":"e_1_2_7_18_1","article-title":"Factors related to the development of communication in CHARGE syndrome","author":"Thelin JW","year":"2005","journal-title":"Am J Med Genet"},{"key":"e_1_2_7_19_1","first-page":"1","article-title":"Infant\u2010toddler information processing assessment for children with pervasive developmental disorder and autism: Part 1","volume":"10","author":"Zelazo PR","year":"1997","journal-title":"Infant Young Child"}],"container-title":["American Journal of Medical Genetics Part A"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fajmg.a.30546","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ajmg.a.30546","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,12]],"date-time":"2023-09-12T13:43:57Z","timestamp":1694526237000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ajmg.a.30546"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,1,7]]},"references-count":18,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2005,3,15]]}},"alternative-id":["10.1002\/ajmg.a.30546"],"URL":"https:\/\/doi.org\/10.1002\/ajmg.a.30546","archive":["Portico"],"relation":{},"ISSN":["1552-4825","1552-4833"],"issn-type":[{"value":"1552-4825","type":"print"},{"value":"1552-4833","type":"electronic"}],"subject":[],"published":{"date-parts":[[2005,1,7]]}}}