{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T10:26:22Z","timestamp":1785839182435,"version":"3.56.0"},"reference-count":25,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2005,3,21]],"date-time":"2005-03-21T00:00:00Z","timestamp":1111363200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["American J of Med Genetics Pt A"],"published-print":{"date-parts":[[2005,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Bifid epiglottis is a rare anomaly, which is heterogeneous and is often associated with other anomalies, particularly polydactyly. It has been reported in 40% of patients with Pallister\u2013Hall syndrome and rarely in other syndromes. We report two brothers with bifid epiglottis who also have features suggestive of Bardet\u2013Biedl syndrome. We also review the features seen in 22 patients reported in the literature with bifid epiglottis. No patient had bifid epiglottis as an isolated anomaly. Other malformations include clefts, micropenis, renal abnormalities, anal malformations, hypospadias, hypothalamic hamartomas, hypopituitarism, heart defects, and Hirschprung disease. Bifid epiglottis may be an under\u2010recognized feature of Bardet\u2013Biedl syndrome and should be considered in these patients, particularly if there are airway symptoms. Many of the anomalies associated with bifid epiglottis have potentially serious consequences and thus, a thorough evaluation of the patient with bifid epiglottis is warranted. \u00a9 2005 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/ajmg.a.30659","type":"journal-article","created":{"date-parts":[[2005,3,21]],"date-time":"2005-03-21T21:50:37Z","timestamp":1111441837000},"page":"447-449","source":"Crossref","is-referenced-by-count":31,"title":["Significance of bifid epiglottis"],"prefix":"10.1002","volume":"134A","author":[{"given":"Cathy A.","family":"Stevens","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joel C.","family":"Ledbetter","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2005,3,21]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1136\/jmg.26.1.49"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1096-8628(19961002)65:1<76::AID-AJMG12>3.0.CO;2-O"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/1294"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1972.00770090252020"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.1320340316"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1177\/000348949610500211"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(85)92759-X"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-197610000-00002"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1177\/000348946707600402"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1097\/00125817-199903000-00008"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1038\/ng0397-266"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0194-59989770365-6"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-194902000-00009"},{"key":"e_1_2_5_15_1","first-page":"493p","volume-title":"The developing human:Clinically oriented embryology","author":"Moore KL","year":"1993"},{"key":"e_1_2_5_16_1","doi-asserted-by":"publisher","DOI":"10.1038\/1711"},{"key":"e_1_2_5_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2990.1985.tb00005.x"},{"key":"e_1_2_5_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/1096-8628(20000904)94:1<64::AID-AJMG13>3.0.CO;2-D"},{"key":"e_1_2_5_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/0165-5876(94)90200-3"},{"key":"e_1_2_5_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/0165-5876(95)01193-F"},{"key":"e_1_2_5_21_1","doi-asserted-by":"publisher","DOI":"10.1177\/000348940111000217"},{"key":"e_1_2_5_22_1","first-page":"235","article-title":"Epiglottide bifida in soggetto polimalformato","volume":"35","author":"Tarateta A","year":"1983","journal-title":"Min Pediatr"},{"key":"e_1_2_5_23_1","first-page":"636","article-title":"Clinical correlation of anomalies of the supraglottic larynx with the staged sequence of normal human laryngeal development","volume":"87","author":"Tucker JA","year":"1978","journal-title":"Ann Otol"},{"key":"e_1_2_5_24_1","doi-asserted-by":"publisher","DOI":"10.1053\/hn.1999.v120.a83517"},{"key":"e_1_2_5_25_1","first-page":"718","article-title":"Beitrag zu den angeboren Missbildungen des Kehlkopfes","volume":"33","author":"Weingaertner M","year":"1920","journal-title":"Arch Laryngol Rhinol"},{"key":"e_1_2_5_26_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215100142240"}],"container-title":["American Journal of Medical Genetics Part A"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fajmg.a.30659","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ajmg.a.30659","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,18]],"date-time":"2023-10-18T14:52:23Z","timestamp":1697640743000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ajmg.a.30659"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,3,21]]},"references-count":25,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2005,5]]}},"alternative-id":["10.1002\/ajmg.a.30659"],"URL":"https:\/\/doi.org\/10.1002\/ajmg.a.30659","archive":["Portico"],"relation":{},"ISSN":["1552-4825","1552-4833"],"issn-type":[{"value":"1552-4825","type":"print"},{"value":"1552-4833","type":"electronic"}],"subject":[],"published":{"date-parts":[[2005,3,21]]}}}