{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,13]],"date-time":"2023-10-13T10:10:26Z","timestamp":1697191826221},"reference-count":30,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2005,6,6]],"date-time":"2005-06-06T00:00:00Z","timestamp":1118016000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["American J of Med Genetics Pt A"],"published-print":{"date-parts":[[2005,7,15]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Individual and maternal characteristics as potential risk factors for having severe mental retardation (SMR) occurring with and without cerebral palsy (CP), epilepsy, or a pervasive developmental disorder (PDD) were explored among a cohort of 119,404 children without Down syndrome born in the California Central Valley in 1992 and 1993. Unadjusted and adjusted relative risks (RRs) and their 95% confidence intervals (CIs) based on the Poisson distribution were used to estimate the risks associated with each individual and maternal factor studied for each SMR diagnostic category. The most notable increased risks for SMR occurring in isolation or with CP or epilepsy was for children born low\u2010birth\u2010weight or preterm who were at a substantially increased risk (RRs 2.6\u20139.9). In contrast, the risk of SMR occurring with a PDD was the greatest among males compared to females (RR\u2009=\u20093.4, 95% CI 1.5, 7.9), Blacks compared to Whites (RR\u2009=\u20095.1, 95% CI 1.7, 15.5), and Asians compared to Whites (RR\u2009=\u20093.9, 95% CI 1.3, 12.0). Etiologic heterogeneity when SMR occurs with a PDD was suggested. \u00a9 2005 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/ajmg.a.30801","type":"journal-article","created":{"date-parts":[[2005,6,6]],"date-time":"2005-06-06T21:18:29Z","timestamp":1118092709000},"page":"152-157","source":"Crossref","is-referenced-by-count":2,"title":["Risks for severe mental retardation occurring in isolation and with other developmental disabilities"],"prefix":"10.1002","volume":"136A","author":[{"given":"Laura L.","family":"Jelliffe\u2010Pawlowski","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gary M.","family":"Shaw","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Verne","family":"Nelson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John A.","family":"Harris","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,6,6]]},"reference":[{"key":"e_1_2_6_2_1","volume-title":"Classification in mental retardation","author":"American Association on Mental Deficiency","year":"1983"},{"key":"e_1_2_6_3_1","volume-title":"Mental retardation: Definition, classification, and systems of support","author":"American Association on Mental Retardation","year":"1997"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.books.9780890423349"},{"key":"e_1_2_6_5_1","first-page":"460","article-title":"Prevalence of major mental retardation and associated disabilities in the Canadian Maritime provinces","volume":"91","author":"Cameron\u2010McQueen PC","year":"1987","journal-title":"Am J Ment Defic"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.107.6.e86"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02172829"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(05)81693-2"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.2105\/AJPH.85.3.329"},{"key":"e_1_2_6_10_1","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1542\/peds.97.4.547","article-title":"The relationship between idiopathic mental retardation and maternal smoking during pregnancy","volume":"97","author":"Drews CD","year":"1996","journal-title":"Pediatrics"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1097\/00004583-199711000-00019"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.158.3.403"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1528-1157.1993.tb02586.x"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1001\/archpedi.157.6.545"},{"key":"e_1_2_6_15_1","unstructured":"Lanterman Act.1969. 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