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The girls, born to healthy non\u2010consanguineous parents, have borderline psychomotor development delay (probably due to hearing defect) and minor dysmorphisms. The clinical picture fits the Chudley\u2013McCullough syndrome, an autosomal recessive condition, to date described in only five families. Our data, in particular the neuroradiological findings, include all brain anomalies variably reported in previous works (hydrocephalus, corpus callosum partial agenesis, interhemispheric cyst, cerebral and cerebellar cortex dysplasia), thus illustrating the full phenotype of the syndrome. \u00a9 2006 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/ajmg.a.31178","type":"journal-article","created":{"date-parts":[[2006,4,26]],"date-time":"2006-04-26T22:55:25Z","timestamp":1146092125000},"page":"1183-1188","source":"Crossref","is-referenced-by-count":11,"title":["Sensorineural deafness, hydrocephalus and structural brain abnormalities in two sisters: The Chudley\u2013McCullough syndrome"],"prefix":"10.1002","volume":"140A","author":[{"given":"Fabio","family":"Matteucci","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Enrico","family":"Tarantino","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria Cristina","family":"Bianchi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cristina","family":"Cingolani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bruno","family":"Fattori","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrea","family":"Nacci","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesco","family":"Ursino","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,4,26]]},"reference":[{"key":"e_1_2_4_2_1","doi-asserted-by":"publisher","DOI":"10.12968\/hmed.2005.66.1.17533"},{"key":"e_1_2_4_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1096-8628(19970131)68:3<350::AID-AJMG19>3.0.CO;2-S"},{"key":"e_1_2_4_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.AUD.0000079802.82344.B5"},{"key":"e_1_2_4_5_1","volume-title":"Hereditary hearing loss and its syndromes. 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