{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,2]],"date-time":"2025-11-02T15:44:40Z","timestamp":1762098280726},"reference-count":26,"publisher":"Wiley","issue":"21","license":[{"start":{"date-parts":[[2006,10,11]],"date-time":"2006-10-11T00:00:00Z","timestamp":1160524800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["American J of Med Genetics Pt A"],"published-print":{"date-parts":[[2006,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The findings in a newborn male with agenesis of parietal bones, gracile long bones, and hypoplasia of the spleen are presented. Although parietal agenesis is unique, the findings are compatible with 18 previously reported cases characterized by cranial hypomineralization, Kleeblatsch\u00e4del, gracile bones, and splenic aplasia\/hypoplasia, the nomenclature for which has been descriptive: gracile bone disorders, \u201costeocraniostenosis,\u201d \u201costeocraniosplenic syndrome.\u201d The term \u201costeocraniostenosis\u201d may be inappropriate in that craniostenosis has been infrequently reported, a feature also of importance with respect to the pathogenesis of the Kleeblatsch\u00e4del. The group likely reflects heterogeneous etiology and pathogenesis. Precedent, however, including animal models, justifies consideration of genetic aberrations, in particular, mutations in homeobox genes. \u00a9 2006 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/ajmg.a.31473","type":"journal-article","created":{"date-parts":[[2006,10,11]],"date-time":"2006-10-11T20:01:20Z","timestamp":1160596880000},"page":"2341-2348","source":"Crossref","is-referenced-by-count":7,"title":["Parietal bone agenesis with gracile bones and splenic hypoplasia\/aplasia: Clinico\u2010pathologic report and differential diagnosis with review of cranio\u2010gracile bone syndromes, \u201costeocraniostenosis\u201d and Kleeblattsch\u00e4del"],"prefix":"10.1002","volume":"140A","author":[{"given":"Gerald S.","family":"Spear","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,10,11]]},"reference":[{"key":"e_1_2_4_2_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2443.2000.00339.x"},{"key":"e_1_2_4_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.1320330304"},{"key":"e_1_2_4_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/00019605-200201000-00012"},{"key":"e_1_2_4_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.1320410426"},{"key":"e_1_2_4_6_1","first-page":"51","volume-title":"Craniosynostosis: Diagnosis, evaluation and management","author":"Cohen MM","year":"2000"},{"key":"e_1_2_4_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1096-8628(19980305)76:2<125::AID-AJMG4>3.0.CO;2-S"},{"key":"e_1_2_4_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/bdra.20231"},{"key":"e_1_2_4_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/00001665-200303000-00010"},{"key":"e_1_2_4_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.1320590421"},{"key":"e_1_2_4_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.a.31326"},{"key":"e_1_2_4_12_1","unstructured":"Holterm\u00fcllerK WiedemannHR.1958.Kleeblattsch\u00e4del\u2010Syndrom. 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