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Within families, critical questions arose of what, when, and to whom to disclose, and what to do post\u2010disclosure. Interviewees wrestled with dilemmas of <jats:italic>what<\/jats:italic> to tell (e.g., suspicions vs. confirmed symptoms; initiation vs. completion of testing; partial vs. indirect information), how to disclose (e.g., planning in advance vs. \u201cblurting out\u201d information in arguments), and whether and how to tell extended family members. Questions arose of <jats:italic>when<\/jats:italic> to tell (i.e., to avoid disclosing \u201ctoo early\u201d or \u201ctoo late\u201d). Similarities and differences emerged related to types of relationships (e.g., parents telling offspring vs. offspring telling parents vs. siblings telling each other). Individuals often disclosed because of perceived duty to foster the health of their family members, enabling these others to pursue appropriate medical evaluation, if desired. Yet tensions arose because the information could burden these members, who also have rights to remain \u201cin denial\u201d if they wish and not discuss the topic or pursue testing. Post\u2010disclosure, dilemmas emerged of whether and how much to encourage family members to pursue testing. These data shed important light on critical issues that have received little, if any, attention concerning what, how, and when disclosure occurs, and have key implications for at\u2010risk individuals, genetic counselors, and other health care workers (HCWs), and for future research. At\u2010risk individuals would benefit from considering these issues in advance. HCWs need to realize that these decisions are multi\u2010faceted. Future research can explore whether, when, how, and how often HCWs raise these issues with individuals. \u00a9 2007 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/ajmg.a.31864","type":"journal-article","created":{"date-parts":[[2007,7,13]],"date-time":"2007-07-13T22:21:54Z","timestamp":1184365314000},"page":"1835-1849","source":"Crossref","is-referenced-by-count":45,"title":["Disclosures of Huntington disease risk within families: Patterns of decision\u2010making and 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