{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T01:08:37Z","timestamp":1790730517939,"version":"4.1.0"},"reference-count":11,"publisher":"Wiley","issue":"24","license":[{"start":{"date-parts":[[2007,10,26]],"date-time":"2007-10-26T00:00:00Z","timestamp":1193356800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["American J of Med Genetics Pt A"],"published-print":{"date-parts":[[2007,12,15]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>We present a series of seven patients who were previously diagnosed with Proteus syndrome, but who do not meet published diagnostic criteria for this disorder and whose natural history is distinct from that of Proteus syndrome. This newly recognized phenotype comprises progressive, complex, and mixed truncal vascular malformations, dysregulated adipose tissue, varying degrees of scoliosis, and enlarged bony structures without progressive bony overgrowth. We have named this condition <jats:italic>c<\/jats:italic>ongenital <jats:italic>l<\/jats:italic>ipomatous <jats:italic>o<\/jats:italic>vergrowth, <jats:italic>v<\/jats:italic>ascular malformations, and <jats:italic>e<\/jats:italic>pidermal nevi (CLOVE syndrome) on a heuristic basis. In contrast to the bony distortion so characteristic of Proteus syndrome, distortion in CLOVE syndrome occurs only following major or radical surgery. Here, we contrast differences and similarities of CLOVE syndrome to Proteus syndrome. \u00a9 2007 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/ajmg.a.32023","type":"journal-article","created":{"date-parts":[[2007,10,26]],"date-time":"2007-10-26T18:42:50Z","timestamp":1193424170000},"page":"2944-2958","source":"Crossref","is-referenced-by-count":220,"title":["Newly delineated syndrome of <i>c<\/i>ongenital <i>l<\/i>ipomatous <i>o<\/i>vergrowth, <i>v<\/i>ascular malformations, and <i>e<\/i>pidermal nevi (CLOVE syndrome) in seven patients"],"prefix":"10.1002","volume":"143A","author":[{"given":"Julie C.","family":"Sapp","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joyce T.","family":"Turner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiddeke M.","family":"van de Kamp","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fleur S.","family":"van Dijk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R. 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A proposito de un caso clinico","author":"Eldredge PMS","year":"1993","journal-title":"Rev Hospital de Ninos Buenos Aires"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1148\/rg.244035726"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.a.30327"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2004.12.047"}],"container-title":["American Journal of Medical Genetics Part A"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fajmg.a.32023","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ajmg.a.32023","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,12]],"date-time":"2023-09-12T15:47:41Z","timestamp":1694533661000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ajmg.a.32023"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,11,28]]},"references-count":11,"journal-issue":{"issue":"24","published-print":{"date-parts":[[2007,12,15]]}},"alternative-id":["10.1002\/ajmg.a.32023"],"URL":"https:\/\/doi.org\/10.1002\/ajmg.a.32023","archive":["Portico"],"relation":{},"ISSN":["1552-4825","1552-4833"],"issn-type":[{"value":"1552-4825","type":"print"},{"value":"1552-4833","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007,11,28]]}}}