{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T00:32:08Z","timestamp":1783384328601,"version":"3.54.6"},"reference-count":9,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2009,8,13]],"date-time":"2009-08-13T00:00:00Z","timestamp":1250121600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["American J of Med Genetics Pt A"],"published-print":{"date-parts":[[2009,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>This article outlines the dental conditions and treatment findings of individuals ranging in age from 4 months to 30 years of age diagnosed with ankyloblepharon\u2010ectodermal dysplasia\u2010cleft lip\/palate (AEC) syndrome. The average number of permanent teeth present is 4.75 with a range of 0\u201312 teeth. The most frequently present permanent teeth are first molars, canines and maxillary incisors. The dentition of AEC\u2010affected individuals in our study is similar to reports in other ectodermal dysplasia syndromes. The dental treatment findings, including those necessitated by the cleft palate defect seen in the syndrome, are also similar to age appropriate treatment seen in other cases of ectodermal dysplasia syndromes. Only 22% of subjects had prosthetic replacement of missing teeth. History indicated that issues related to treatment of the palatal cleft and lack of recognition of the oral defects as a part of the underlying medical problem were factors in receiving comprehensive tooth replacement care. \u00a9 2009 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/ajmg.a.32790","type":"journal-article","created":{"date-parts":[[2009,8,13]],"date-time":"2009-08-13T18:27:29Z","timestamp":1250188049000},"page":"1907-1909","source":"Crossref","is-referenced-by-count":17,"title":["Oral findings in ankyloblepharon\u2010ectodermal dysplasia\u2010cleft lip\/palate (AEC) syndrome"],"prefix":"10.1002","volume":"149A","author":[{"given":"Frank","family":"Farrington","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leonard","family":"Lausten","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2009,8,13]]},"reference":[{"key":"e_1_2_7_2_1","first-page":"77","volume-title":"Consensus conference on ectodermal dysplasia with special reference to dental treatment","author":"Bergendal B","year":"1998"},{"key":"e_1_2_7_3_1","first-page":"278","article-title":"Pattern of permanent teeth present in individuals with ectodermal dysplasia and severe hypodontia suggests treatment with dental implants","volume":"20","author":"Guckes A","year":"1998","journal-title":"Pediatr Dent"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1976.tb04384.x"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.prosdent.2006.03.002"},{"key":"e_1_2_7_6_1","volume-title":"Parameters of oral health care for individuals affected by ectodermal dysplasia syndromes","author":"NFED Scientific Advisory Board","year":"2007"},{"key":"e_1_2_7_7_1","first-page":"13","volume-title":"Consensus conference on ectodermal dysplasia with special reference to dental treatment","author":"Pirinen S","year":"1998"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-849X.2006.00173.x"},{"key":"e_1_2_7_9_1","first-page":"332","volume-title":"Recognized pattern's of human malformations","author":"Smith D","year":"2006"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-263X.2005.00610.x"}],"container-title":["American Journal of Medical Genetics Part A"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fajmg.a.32790","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ajmg.a.32790","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,13]],"date-time":"2023-09-13T05:23:04Z","timestamp":1694582584000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ajmg.a.32790"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,8,13]]},"references-count":9,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2009,9]]}},"alternative-id":["10.1002\/ajmg.a.32790"],"URL":"https:\/\/doi.org\/10.1002\/ajmg.a.32790","archive":["Portico"],"relation":{},"ISSN":["1552-4825","1552-4833"],"issn-type":[{"value":"1552-4825","type":"print"},{"value":"1552-4833","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,8,13]]}}}