{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T14:27:28Z","timestamp":1786976848834,"version":"build-2736575974"},"reference-count":20,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2009,10,19]],"date-time":"2009-10-19T00:00:00Z","timestamp":1255910400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["American J of Med Genetics Pt A"],"published-print":{"date-parts":[[2009,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Simpson\u2013Golabi\u2013Behmel syndrome is an X\u2010linked recessive overgrowth disorder characterized by prenatal onset of overgrowth, characteristic facies, and frequently mild to severe mental retardation. In addition, a number of other characteristics including supernumerary nipples, a grooved tongue or chin, chest wall malformations, and mild genital anomalies are frequently seen as well. Here we present three brothers with Simpson\u2013Golabi\u2013Behmel syndrome, all of which had cryptorchidism with one also having chordee of the penis, hypospadius, and penoscrotal transposition. While severe genital anomalies have been reported rarely in patients with Simpson\u2013Golabi\u2013Behmel syndrome, no individuals with such anomalies prior to this report had survived beyond the neonatal period. \u00a9 2009 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/ajmg.a.33047","type":"journal-article","created":{"date-parts":[[2009,10,19]],"date-time":"2009-10-19T16:33:50Z","timestamp":1255970030000},"page":"2484-2488","source":"Crossref","is-referenced-by-count":15,"title":["Genital anomalies in three male siblings with Simpson\u2013Golabi\u2013Behmel syndrome"],"prefix":"10.1002","volume":"149A","author":[{"given":"Christopher B.","family":"Griffith","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard C.","family":"Probert","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gail H.","family":"Vance","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2009,10,28]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1086\/302527"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.1320460523"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/pmic.200600654"},{"key":"e_1_2_5_5_1","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1093\/oso\/9780195118612.003.0011","volume-title":"Syndromes of the head and neck","author":"Gorlin RJ","year":"2001"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.1320290406"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.1320440203"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1096-8628(19961211)66:2<227::AID-AJMG20>3.0.CO;2-U"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.1320430165"},{"key":"e_1_2_5_10_1","first-page":"160","volume-title":"Smith's recognizable patterns of human malformation","author":"Jones KL","year":"2006"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1054\/bjom.1999.0186"},{"key":"e_1_2_5_12_1","first-page":"633","article-title":"Human male sex determination and sexual differentiation: Pathways, molecular interactions and genetic disorders","volume":"41","author":"Ku\u010dinskas L","year":"2005","journal-title":"Medicina (Kaunas)"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1136\/jmg.34.6.480"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1515\/JPEM.2003.16.2.225"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/s100380050170"},{"key":"e_1_2_5_16_1","doi-asserted-by":"publisher","DOI":"10.1038\/ng0396-241"},{"key":"e_1_2_5_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-0004.2007.00871.x"},{"key":"e_1_2_5_18_1","first-page":"574","article-title":"Simpson\u2010Golabi\u2010Behmel syndrome and attention deficit hyperactivity disorder in two brothers","volume":"36","author":"Savarirayan R","year":"1999","journal-title":"J Med Genet"},{"key":"e_1_2_5_19_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.1320590310"},{"key":"e_1_2_5_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-0004.1995.tb04307.x"},{"key":"e_1_2_5_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pediatrneurol.2005.07.008"}],"container-title":["American Journal of Medical Genetics Part A"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fajmg.a.33047","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ajmg.a.33047","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,3,17]],"date-time":"2024-03-17T02:09:03Z","timestamp":1710641343000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ajmg.a.33047"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,10,28]]},"references-count":20,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2009,11]]}},"alternative-id":["10.1002\/ajmg.a.33047"],"URL":"https:\/\/doi.org\/10.1002\/ajmg.a.33047","archive":["Portico"],"relation":{},"ISSN":["1552-4825","1552-4833"],"issn-type":[{"value":"1552-4825","type":"print"},{"value":"1552-4833","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,10,28]]}}}