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We report on three patients presenting with tibial hypo\/aplasia associated with either femoral bifurcation or radial ray defect following prenatal exposure to VA. Femoral bifurcation and tibial agenesis has been described in the Gollop\u2013Wolfgang complex and in the tibial agenesis\u2010ectrodactyly syndrome. Tibial agenesis has also been reported in VACTERL association. The relation between prenatal exposure to VA and tibial agenesis is discussed. \u00a9 2010 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/ajmg.a.33633","type":"journal-article","created":{"date-parts":[[2010,10,14]],"date-time":"2010-10-14T16:17:22Z","timestamp":1287073042000},"page":"2805-2809","source":"Crossref","is-referenced-by-count":11,"title":["Tibial developmental field defect in valproic acid embryopathy: Report on three 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