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Non\u2010syndromic cases of microtia were compared to non\u2010malformed, population\u2010based liveborn control infants, by estimating adjusted odds ratios (AORs) and 95% confidence intervals (CIs) from logistic regression models that included maternal race\/ethnicity, education, and study site. Maternal obesity was only weakly associated with microtia. Maternal periconceptional intake of folic\u2010acid\u2010containing vitamin supplements reduced the risk for microtia, but only among non\u2010obese women (OR: 0.63; 95% CI: 0.44\u20130.91). The reduced risk was stronger when analyses were restricted to isolated cases (OR: 0.51; 95% CI: 0.34\u20130.77), and it was independent of the level of maternal dietary folate intake. Adjusting for maternal race\/ethnicity did not reveal alternative interpretations of this association. This analysis suggests that maternal periconceptional intake of folic\u2010acid\u2010containing supplements may provide protection from microtia for non\u2010obese women. \u00a9 2010 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/ajmg.a.33694","type":"journal-article","created":{"date-parts":[[2010,10,14]],"date-time":"2010-10-14T16:35:34Z","timestamp":1287074134000},"page":"2756-2761","source":"Crossref","is-referenced-by-count":29,"title":["Association of microtia with maternal obesity and periconceptional folic acid use"],"prefix":"10.1002","volume":"152A","author":[{"given":"Chen","family":"Ma","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Suzan L.","family":"Carmichael","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Angela E.","family":"Scheuerle","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mark 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