{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T12:56:52Z","timestamp":1790081812186,"version":"4.0.1"},"reference-count":34,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2015,9,1]],"date-time":"2015-09-01T00:00:00Z","timestamp":1441065600000},"content-version":"tdm","delay-in-days":1631,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Am. J. Med. Genet."],"published-print":{"date-parts":[[2011,4]]},"DOI":"10.1002\/ajmg.a.33934","type":"journal-article","created":{"date-parts":[[2011,3,15]],"date-time":"2011-03-15T20:44:04Z","timestamp":1300221844000},"page":"748-756","source":"Crossref","is-referenced-by-count":39,"title":["An additional patient with mycophenolate mofetil embryopathy: Cardiac and facial analyses"],"prefix":"10.1002","volume":"155","author":[{"given":"Angela E.","family":"Lin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kathryn E.","family":"Singh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arthur","family":"Strauss","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Son","family":"Nguyen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kristyn","family":"Rawson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Virginia E.","family":"Kimonis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2011,3,15]]},"reference":[{"key":"10.1002\/ajmg.a.33934-BIB1|cit2","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1002\/1096-8628(20010301)99:2<124::AID-AJMG1114>3.0.CO;2-9","article-title":"Temporal bone anomaly proposed as a major criteria for diagnosis of CHARGE syndrome","volume":"99","author":"Amiel","year":"2001","journal-title":"Am J Med Genet"},{"key":"10.1002\/ajmg.a.33934-BIB2|cit3","doi-asserted-by":"crossref","first-page":"1241","DOI":"10.1002\/ajmg.a.32685","article-title":"Reviewing the evidence for mycophenolate mofetil as a new teratogen: Case report and review of the literature","volume":"149A","author":"Anderka","year":"2009","journal-title":"Am J Med Genet Part A"},{"key":"10.1002\/ajmg.a.33934-BIB3|cit4","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1097\/TP.0b013e31817cf28a","article-title":"Even low dose of mycophenolate mofetil in a mother recipient of heart transplant can seriously damage the fetus","volume":"86","author":"Andrade Vila","year":"2008","journal-title":"Transplantation"},{"key":"10.1002\/ajmg.a.33934-BIB4|cit5","doi-asserted-by":"crossref","first-page":"1963","DOI":"10.1002\/ajmg.a.32420","article-title":"Mycophenolate mofetil embryopathy may be dose and timing dependent","volume":"146A","author":"Ang","year":"2008","journal-title":"Am J Med Genet Part A"},{"key":"10.1002\/ajmg.a.33934-BIB5|cit6","first-page":"103","volume-title":"Clinical transplants 2004","author":"Armenti","year":"2004"},{"key":"10.1002\/ajmg.a.33934-BIB6|cit7","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1097\/01.AOG.0000303106.97639.6f","article-title":"Where observation is concerned, chance favors only the prepared mind","volume":"111","author":"Carey","year":"2008","journal-title":"Obstet Gynecol"},{"key":"10.1002\/ajmg.a.33934-BIB7|cit8","doi-asserted-by":"crossref","first-page":"1407","DOI":"10.1016\/j.transproceed.2009.03.088","article-title":"A case of coloboma in a newborn to a woman taking mycophenolate mofetil in pregnancy after kidney transplantation","volume":"41","author":"Dei Malatesta","year":"2009","journal-title":"Transplant Proc"},{"key":"10.1002\/ajmg.a.33934-BIB8|cit9","doi-asserted-by":"crossref","first-page":"2722","DOI":"10.1093\/ndt\/gfm253","article-title":"Fetal malformations associated with mycophenolate mofetil for lupus nephritis","volume":"22","author":"El Sebaaly","year":"2007","journal-title":"Nephrol Dial Transplant"},{"key":"10.1002\/ajmg.a.33934-BIB9|cit10","unstructured":"Heike CL Hing AV 2010 Craniofacial microsomia overview. GeneReviews. Posted March 19, 2009. Accessioned September 9, 2010"},{"key":"10.1002\/ajmg.a.33934-BIB10|cit11","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1597\/1545-1569(1995)032<0405:OPAOCA>2.3.CO;2","article-title":"OMENS-Plus: analysis of craniofacial and extracraniofacial anomalies in hemifacial microsomia","volume":"32","author":"Horgan","year":"1995","journal-title":"Cleft Palate Craniofac J"},{"key":"10.1002\/ajmg.a.33934-BIB11|cit12","doi-asserted-by":"crossref","first-page":"e6","DOI":"10.1016\/j.ajog.2008.04.008","article-title":"Sonographic diagnosis of fetal malformations associated with mycophenolate mofetil exposure in utero","volume":"199","author":"Huang","year":"2008","journal-title":"Am J Obstet Gynecol"},{"key":"10.1002\/ajmg.a.33934-BIB12|cit13","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1002\/ajmg.a.32599","article-title":"Elements of morphology: Standard terminology for the ear","volume":"149A","author":"Hunter","year":"2009","journal-title":"Am J Med Genet Part A"},{"key":"10.1002\/ajmg.a.33934-BIB13|cit14","doi-asserted-by":"crossref","first-page":"1231","DOI":"10.1002\/ajmg.a.32715","article-title":"Intrauterine exposure to mycophenolate mofetil and multiple congenital anomalies in a newborn: Possible teratogenic effect","volume":"149A","author":"Jackson","year":"2009","journal-title":"Am J Med Genet Part A"},{"key":"10.1002\/ajmg.a.33934-BIB14|cit15","doi-asserted-by":"crossref","first-page":"904","DOI":"10.1111\/j.1471-0528.2005.00607.x","article-title":"Pregnancy outcome after maternal organ transplantation in Sweden","volume":"112","author":"K\u00e4ll\u00e9n","year":"2005","journal-title":"Br J Obstet Gynaecol"},{"key":"10.1002\/ajmg.a.33934-BIB15|cit16","first-page":"794","article-title":"Prenatal exposure to mycophenolate mofetil: An updated estimate","volume":"32","author":"Klieger-Grossman","year":"2010","journal-title":"JOGC"},{"key":"10.1002\/ajmg.a.33934-BIB16|cit17","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1111\/j.1440-1797.2009.01153.x","article-title":"Congenital malformations with low-dose mycophenolate mofetil after kidney transplantation","volume":"15","author":"Koshy","year":"2010","journal-title":"Nephrology"},{"key":"10.1002\/ajmg.a.33934-BIB17|cit18","first-page":"292","article-title":"Preliminary observations on isoretinoin-induced ear malformations and pattern formation of the external ear","volume":"11","author":"Lammer","year":"1991","journal-title":"J Craniofac Genet Dev Biol"},{"key":"10.1002\/ajmg.a.33934-BIB18|cit19","doi-asserted-by":"crossref","first-page":"1091","DOI":"10.1097\/01.AOG.0000124986.32858.ba","article-title":"Mycophenolate mofetil in pregnancy after renal transplantation: A case of major fetal malformations","volume":"103","author":"Le Ray","year":"2004","journal-title":"Obstet Gynecol"},{"key":"10.1002\/ajmg.a.33934-BIB19|cit20","first-page":"85","volume-title":"Human malformations and related anomalies","author":"Lin","year":"2006"},{"key":"10.1002\/ajmg.a.33934-BIB20|cit21","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/j.reprotox.2009.02.007","article-title":"Tetrada of the possible mycophenolate mofetil embryopathy: A review","volume":"28","author":"Merlob","year":"2009","journal-title":"Repro Toxicol"},{"key":"10.1002\/ajmg.a.33934-BIB21|cit22","first-page":"22","article-title":"Genotype-phenotype analysis of the branchio-oculo-facial syndrome","volume":"155A","author":"Milunsky","year":"2010","journal-title":"Am J Med Genet A"},{"key":"10.1002\/ajmg.a.33934-BIB22|cit23","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1136\/jmg.2008.057984","article-title":"Double outlet right ventricle: Aetiologies and associations","volume":"45","author":"Obler","year":"2008","journal-title":"J Med Genet"},{"key":"10.1002\/ajmg.a.33934-BIB23|cit24","doi-asserted-by":"crossref","first-page":"1237","DOI":"10.1002\/ajmg.a.32684","article-title":"Congenital diaphragmatic hernia and microtia in a newborn with mycophenolate mofetil (MMF) exposure: Phenocopy for Fryns syndrome or broad spectrum of teratogenic effects?","volume":"149A","author":"Parisi","year":"2009","journal-title":"Am J Med Genet Part A"},{"key":"10.1002\/ajmg.a.33934-BIB24|cit25","doi-asserted-by":"crossref","first-page":"1853","DOI":"10.1002\/ajmg.a.32950","article-title":"Syndromes of the first and second pharyngeal arches: A review","volume":"149A","author":"Passos-Bueno","year":"2009","journal-title":"Am J Med Genet Part A"},{"key":"10.1002\/ajmg.a.33934-BIB25|cit26","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1002\/ajmg.a.32117","article-title":"In utero exposure to mycophenolate mofetil: A characteristic phenotype?","volume":"146A","author":"Perez-Aytes","year":"2008","journal-title":"Am J Med Genet Part A"},{"key":"10.1002\/ajmg.a.33934-BIB26|cit27","doi-asserted-by":"crossref","first-page":"994","DOI":"10.1097\/00007890-200104150-00028","article-title":"Kidney transplantation during the first trimester of pregnancy: Immunosuppression with mycophenolate mofetil, tacrolimus, and prednisone","volume":"71","author":"P\u00e9rgola","year":"2001","journal-title":"Transplantation"},{"key":"10.1002\/ajmg.a.33934-BIB27|cit28","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1097\/01.AOG.0000298347.18812.a4","article-title":"Severe facial clefts in acrofacial dystosis: A consequence of prenatal exposure to mycophenolate mofetil?","volume":"111","author":"Schoner","year":"2008","journal-title":"Obstet Gynecol"},{"key":"10.1002\/ajmg.a.33934-BIB28|cit29","doi-asserted-by":"crossref","first-page":"1698","DOI":"10.1097\/01.tp.0000252683.74584.29","article-title":"Pregnancy outcomes in solid organ transplant with exposure to mycophenolate mofetil or sirolimus","volume":"82","author":"Sifontis","year":"2006","journal-title":"Transplantation"},{"key":"10.1002\/ajmg.a.33934-BIB29|cit30","doi-asserted-by":"crossref","first-page":"2141","DOI":"10.1002\/ajmg.a.33015","article-title":"Confirmation of TFAP2A gene involvement in branchio-oculo-facial syndrome (BOFS) and report of temporal bone anomalies","volume":"149A","author":"Stoetzel","year":"2009","journal-title":"Am J Med Genet A"},{"key":"10.1002\/ajmg.a.33934-BIB30|cit31","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1002\/ajmg.a.32619","article-title":"A complex TFAP2A allele is associated with branchio-oculo-facial syndrome and inner ear malformation in a deaf child","volume":"149A","author":"Tekin","year":"2009","journal-title":"Am J Med Genet A"},{"key":"10.1002\/ajmg.a.33934-BIB31|cit32","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1038\/sj.jp.7211631","article-title":"Neonatal anemia and hydrops fetalis after maternal mycophenolate mofetil use","volume":"27","author":"Tjeertes","year":"2007","journal-title":"J Perinatol"},{"key":"10.1002\/ajmg.a.33934-BIB32|cit33","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1097\/MCD.0b013e3282efef5b","article-title":"The fetal mycophenolate mofetil syndrome","volume":"17","author":"Velinov","year":"2008","journal-title":"Clin Dysmorphol"},{"key":"10.1002\/ajmg.a.33934-BIB33|cit34","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1597\/1545-1569(1991)028<0068:TOMENS>2.3.CO;2","article-title":"The O.M.E.N.S. classification of hemifacial microsomia","volume":"28","author":"Vento","year":"1991","journal-title":"Cleft Palate Craniofac J"},{"key":"10.1002\/ajmg.a.33934-BIB34|cit35","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1542\/peds.2008-0348","article-title":"Mycophenolate mofetil during pregnancy: Some words of caution","volume":"122","author":"Vento","year":"2008","journal-title":"Pediatrics"}],"container-title":["American Journal of Medical Genetics Part A"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fajmg.a.33934","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/onlinelibrary.wiley.com\/wol1\/doi\/10.1002\/ajmg.a.33934\/fullpdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,6,30]],"date-time":"2021-06-30T20:00:33Z","timestamp":1625083233000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ajmg.a.33934"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,3,15]]},"references-count":34,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2011,4]]}},"URL":"https:\/\/doi.org\/10.1002\/ajmg.a.33934","relation":{},"ISSN":["1552-4825"],"issn-type":[{"value":"1552-4825","type":"print"}],"subject":[],"published":{"date-parts":[[2011,3,15]]}}}