{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,12]],"date-time":"2026-04-12T08:26:58Z","timestamp":1775982418889,"version":"3.50.1"},"reference-count":19,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2012,8,7]],"date-time":"2012-08-07T00:00:00Z","timestamp":1344297600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["American J of Med Genetics Pt A"],"published-print":{"date-parts":[[2012,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>To date, an interstitial deletion of 9p13 has been described only two times in the medical literature. These reports were based on routine chromosomal analysis. We report on two additional patients with an interstitial deletion of 9p13 further defined on array CGH who share clinical features with the other two patients previously described. Our first patient is a 16\u2010year\u2010old girl with a 5.9\u2009Mb deletion at 9p13.3\u20139p13.1, initially detected on routine karyotype analysis and further characterized on array CGH. Our second patient is a 7\u00bd\u2010year\u2010old boy with a 4.8\u2009Mb deletion also at 9p13.3\u20139p13.1. Patients with 9p13 deletion appear to have mild to moderate developmental delay, social and interactive personality, behavior issues such as attention deficit\u2010hyperactivity disorder, short stature, prominent antihelices, hypoplastic nails, and precocious\/early puberty. Our 16\u2010year\u2010old patient is the oldest patient described thus far. This report further characterizes this condition and helps to delineate the long\u2010term prognosis in these patients. \u00a9 2012 Wiley Periodicals, Inc.<\/jats:p>","DOI":"10.1002\/ajmg.a.35536","type":"journal-article","created":{"date-parts":[[2012,8,7]],"date-time":"2012-08-07T19:59:30Z","timestamp":1344369570000},"page":"2328-2335","source":"Crossref","is-referenced-by-count":11,"title":["Report of two patients and further characterization of interstitial 9p13 deletion\u2014A rare but recurrent microdeletion syndrome?"],"prefix":"10.1002","volume":"158A","author":[{"given":"Anna\u2010Kaisa","family":"Niemi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrea","family":"Kwan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Louanne","family":"Hudgins","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Athena M.","family":"Cherry","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Melanie A.","family":"Manning","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2012,8,7]]},"reference":[{"key":"e_1_2_6_2_1","first-page":"17","article-title":"Deletion of the short arm of chromosome no. 9 (46,9p\u2010): A new deletion syndrome","volume":"16","author":"Alfi O","year":"1973","journal-title":"Ann Genet"},{"key":"e_1_2_6_3_1","first-page":"11","article-title":"The 9p\u2010 syndrome","volume":"19","author":"Alfi OS","year":"1976","journal-title":"Ann Genet"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1096-8628(19961111)65:4<277::AID-AJMG6>3.0.CO;2-M"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1038\/ejhg.2009.70"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1006\/geno.2000.6160"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1177\/088307380201700113"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1086\/302016"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-0004.1994.tb04241.x"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1086\/302017"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.1320110208"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1136\/jmg.25.11.741"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2010.11.036"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1097\/00125817-200007000-00006"},{"key":"e_1_2_6_15_1","unstructured":"KimonisV DonkervoortS WattsK.(Updated July 28 2011). 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