{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T15:45:55Z","timestamp":1787931955514,"version":"build-2784847793"},"reference-count":15,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2014,3,7]],"date-time":"2014-03-07T00:00:00Z","timestamp":1394150400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["American J of Med Genetics Pt A"],"published-print":{"date-parts":[[2014,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:label\/><jats:p>Yunis\u2013Varon syndrome is a rare autosomal recessive condition initially characterized by specific skeletal and ectodermal abnormalities, and a poor prognosis, due to neurological and cardiovascular involvement. We describe the cardiovascular and endocrine complications in a 26\u2010year\u2010old man who had been reported previously, adding dilated cardiomyopathy to the clinical features consistent with Yunis\u2013Varon syndrome. Short stature, successfully treated with growth hormone, and hypertension secondary to bilateral renal artery stenosis expand the phenotype. \u00a9 2014 Wiley Periodicals, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ajmg.a.35741","type":"journal-article","created":{"date-parts":[[2014,3,7]],"date-time":"2014-03-07T17:24:50Z","timestamp":1394213090000},"page":"1213-1217","source":"Crossref","is-referenced-by-count":4,"title":["Yunis\u2013varon syndrome: Further delineation of cardiovascular and endocrine outcome"],"prefix":"10.1002","volume":"164","author":[{"given":"P.","family":"Varghese","sequence":"first","affiliation":[{"name":"Cardiovascular Unit Division of Medicine John Hunter Hospital New Lambton NSW Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N.","family":"Collins","sequence":"additional","affiliation":[{"name":"Cardiovascular Unit Division of Medicine John Hunter Hospital New Lambton NSW Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.","family":"Warner","sequence":"additional","affiliation":[{"name":"Cardiovascular Unit Division of Medicine John Hunter Hospital New Lambton NSW Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Leitch","sequence":"additional","affiliation":[{"name":"Cardiovascular Unit Division of Medicine John Hunter Hospital New Lambton NSW Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"Ho","sequence":"additional","affiliation":[{"name":"Department of Orthopedics John Hunter Children's Hospital New Lambton NSW Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"Crock","sequence":"additional","affiliation":[{"name":"Department of Endocrinology and Diabetes John Hunter Children's Hospital New Lambton NSW Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2014,3,7]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1136\/jmg.30.9.788"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.a.32135"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/0960-8966(94)00089-R"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2007-1189"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199608293350915"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1136\/jmg.27.2.114"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1136\/jmg.26.1.55"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.1320140318"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2004-0072"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1058-9813(00)00064-3"},{"key":"e_1_2_5_12_1","first-page":"224","article-title":"Cardiomyopathy added to the Yunis\u2013Varon syndrome","volume":"7","author":"Partington MW","year":"1988","journal-title":"Proc Greenwood Genetic Centre"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejmg.2011.09.002"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2005-0981"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/1096-8628(20001113)95:2<157::AID-AJMG12>3.0.CO;2-E"},{"key":"e_1_2_5_16_1","doi-asserted-by":"publisher","DOI":"10.1001\/archpedi.1980.02130190017005"}],"container-title":["American Journal of Medical Genetics Part A"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fajmg.a.35741","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ajmg.a.35741","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,6]],"date-time":"2023-10-06T16:01:58Z","timestamp":1696608118000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ajmg.a.35741"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,3,7]]},"references-count":15,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2014,5]]}},"alternative-id":["10.1002\/ajmg.a.35741"],"URL":"https:\/\/doi.org\/10.1002\/ajmg.a.35741","archive":["Portico"],"relation":{},"ISSN":["1552-4825","1552-4833"],"issn-type":[{"value":"1552-4825","type":"print"},{"value":"1552-4833","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,3,7]]}}}