{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,19]],"date-time":"2026-02-19T08:10:35Z","timestamp":1771488635244,"version":"3.50.1"},"reference-count":23,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2013,3,13]],"date-time":"2013-03-13T00:00:00Z","timestamp":1363132800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["American J of Med Genetics Pt A"],"published-print":{"date-parts":[[2013,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:label\/><jats:p>Interstitial deletions of 18q lead to a number of phenotypic features, including multiple types of foot deformities. Many of these associated phenotypes have had their critical regions narrowly defined. Here we report on three patients with small overlapping deletions of chromosome 18q determined by microarray analysis (chr18:72493281\u201373512553 hg19 coordinates). All of the patients have congenital vertical talus (CVT). Based on these findings and previous reports in the literature and databases, we narrow the critical region for CVT to a minimum of five genes (<jats:italic>ZNF407<\/jats:italic>, <jats:italic>ZADH2<\/jats:italic>, <jats:italic>TSHZ1<\/jats:italic>, <jats:italic>C18orf62<\/jats:italic>, and <jats:italic>ZNF516<\/jats:italic>), and propose that <jats:italic>TSHZ1<\/jats:italic> is the likely causative gene for CVT in 18q deletion syndrome. \u00a9 2013 Wiley Periodicals, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ajmg.a.35791","type":"journal-article","created":{"date-parts":[[2013,3,14]],"date-time":"2013-03-14T09:32:13Z","timestamp":1363253533000},"page":"1117-1121","source":"Crossref","is-referenced-by-count":11,"title":["Narrowing the Critical Region for Congenital Vertical Talus in Patients With Interstitial 18q Deletions"],"prefix":"10.1002","volume":"161","author":[{"given":"Paul R.","family":"Mark","sequence":"first","affiliation":[{"name":"Department of Medical Genetics Spectrum Health Grand Rapids, Michigan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brian C.","family":"Radlinski","sequence":"additional","affiliation":[{"name":"Michigan State University College of Human Medicine Grand Rapids, Michigan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nathalie","family":"Core","sequence":"additional","affiliation":[{"name":"Institut de Biologie du D\u00e9veloppement de Marseille\u2010Luminy (IBDML) UMR6216, CNRS, Universit\u00e9 de la M\u00e9diterran\u00e9e Marseille Cedex France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alan","family":"Fryer","sequence":"additional","affiliation":[{"name":"Cheshire and Merseyside Regional Clinical Genetics Department The Countess of Chester Hospital NHS Foundation Trust Liverpool United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Edwin P.","family":"Kirk","sequence":"additional","affiliation":[{"name":"Department of Medical Genetics Sydney Children's Hospital Sydney, New South Wales Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chad R.","family":"Haldeman\u2010Englert","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Section on Medical Genetics, Wake Forest School of Medicine Winston\u2010Salem, North Carolina"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2013,3,13]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/0925-4773(96)00594-1"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1096-8628(19990827)85:5<455::AID-AJMG5>3.0.CO;2-Z"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.a.32899"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ydbio.2007.05.038"},{"key":"e_1_2_5_6_1","first-page":"579","article-title":"Partial deletion of the long arms of the chromosome 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