{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,9,10]],"date-time":"2024-09-10T13:22:34Z","timestamp":1725974554886},"reference-count":18,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2013,4,23]],"date-time":"2013-04-23T00:00:00Z","timestamp":1366675200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["American J of Med Genetics Pt A"],"published-print":{"date-parts":[[2013,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:label \/><jats:p>This article reports on an association between Burkitt lymphoma and Noonan syndrome (NS) due to a <jats:italic>RAF1<\/jats:italic> gene mutation. The patient was a 7\u2010year\u2010old boy with NS, who was included in the first series reporting the association between Noonan and <jats:italic>RAF1<\/jats:italic>, and who later presented with a 2\u2010week history of asymptomatic unilateral tonsillar swelling and ipsilateral cervical lymphadenopathy. Histological and biological examinations of the tonsillar biopsy led to the diagnosis of Burkitt lymphoma. While there is a well\u2010established association between NS and solid cell tumors, this is the first case described in the literature of Burkitt lymphoma in a patient with NS, and adds to the growing list of data supporting neoplasia's association with NS. \u00a9 2013 Wiley Periodicals, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ajmg.a.35875","type":"journal-article","created":{"date-parts":[[2013,4,23]],"date-time":"2013-04-23T19:48:26Z","timestamp":1366746506000},"page":"1401-1404","source":"Crossref","is-referenced-by-count":6,"title":["A boy with Burkitt lymphoma associated with Noonan syndrome due to a mutation in <i>RAF1<\/i>"],"prefix":"10.1002","volume":"161","author":[{"given":"Paola","family":"Cianci","sequence":"first","affiliation":[{"name":"Pediatric Genetic Unit, Pediatric Department at Monza Brianza per il Bambino e la sua Mamma (MBBM) Foundation S.Gerardo Hospital Monza Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Valentina","family":"Tono","sequence":"additional","affiliation":[{"name":"Pediatric Genetic Unit, Pediatric Department at Monza Brianza per il Bambino e la sua Mamma (MBBM) Foundation S.Gerardo Hospital Monza Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alessandra","family":"Sala","sequence":"additional","affiliation":[{"name":"Pediatric Hematology\u2010Oncology Unit, Pediatric Department of MBBM Foundation S. Gerardo Hospital Monza Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laura","family":"Locatelli","sequence":"additional","affiliation":[{"name":"Pediatric Hematology\u2010Oncology Unit, Pediatric Department of MBBM Foundation S. Gerardo Hospital Monza Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claudio","family":"Carta","sequence":"additional","affiliation":[{"name":"Department of Hematology, Oncology and Molecular Medicine Istituto Superiore di Sanit\u00e0 Rome Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carmelo","family":"Rizzari","sequence":"additional","affiliation":[{"name":"Pediatric Hematology\u2010Oncology Unit, Pediatric Department of MBBM Foundation S. 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Gerardo Hospital Monza Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Angelo","family":"Selicorni","sequence":"additional","affiliation":[{"name":"Pediatric Genetic Unit, Pediatric Department at Monza Brianza per il Bambino e la sua Mamma (MBBM) Foundation S.Gerardo Hospital Monza Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2013,4,23]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1977.03270370065026"},{"key":"e_1_2_5_3_1","doi-asserted-by":"crossref","first-page":"2736","DOI":"10.1182\/blood-2006-07-036665","article-title":"FAB LMB96 International Study Committee Results of a randomized international study of high\u2010risk central nervous system B non\u2010Hodgkin lymphoma and B acute lymphoblastic leukemia in children and adolescents","volume":"109","author":"Cairo MS","year":"2007","journal-title":"Blood"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/pbc.20527"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/00043426-199911000-00014"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/gcc.20735"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1634\/theoncologist.11-4-375"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.c.30300"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajhg.2010.06.015"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2010.32.8161"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1177\/000992289403300907"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1038\/ng2073"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2006-07-036673"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1038\/ng2078"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrc2109"},{"key":"e_1_2_5_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.2010.05790.x"},{"key":"e_1_2_5_17_1","doi-asserted-by":"publisher","DOI":"10.1097\/00062752-200401000-00007"},{"key":"e_1_2_5_18_1","doi-asserted-by":"publisher","DOI":"10.1159\/000276766"},{"key":"e_1_2_5_19_1","doi-asserted-by":"publisher","DOI":"10.1186\/1750-1172-2-4"}],"container-title":["American Journal of Medical Genetics Part A"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fajmg.a.35875","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ajmg.a.35875","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,30]],"date-time":"2023-10-30T14:42:10Z","timestamp":1698676930000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ajmg.a.35875"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,4,23]]},"references-count":18,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2013,6]]}},"alternative-id":["10.1002\/ajmg.a.35875"],"URL":"https:\/\/doi.org\/10.1002\/ajmg.a.35875","archive":["Portico"],"relation":{},"ISSN":["1552-4825","1552-4833"],"issn-type":[{"value":"1552-4825","type":"print"},{"value":"1552-4833","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,4,23]]}}}