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Molecular genetic testing of<jats:italic>FGFR1<\/jats:italic>,<jats:italic>FGFR2<\/jats:italic>,<jats:italic>FGFR3<\/jats:italic>and<jats:italic>TWIST1<\/jats:italic>genes failed to detect any additional mutations. There are several reports of achondroplasia with associated craniosynostosis, but no other cases of scaphocephaly in children with achondroplasia have been described. Recently it has been demonstrated that<jats:italic>FGFR3<\/jats:italic>mutations affect not only endochondral ossification but also membranous ossification, providing new explanations for the craniofacial hallmarks in achondroplasia. 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