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Parents and carers of 38 individuals with Sotos syndrome (mean age\u2009=\u200917.3; SD\u2009=\u20099.36), completed questionnaires regarding self\u2010injury, aggression, repetitive behavior, autism spectrum phenomenology, overactivity, impulsivity and mood, interest and pleasure. Individuals with Sotos syndrome showed an increased risk of self\u2010injurious behavior, physical aggression, and destruction of property relative to the Down syndrome group but not a greater risk of stereotyped behavior. Impulsivity and levels of activity were also significantly higher relative to those with Down syndrome and comparable to those with ASD. A large proportion of participants met the cut off score for ASD (70.3%) and Autism (32.4%) on the Social Communication Questionnaire. Social impairments were particularly prominent with repetitive behavior and communication impairments less characteristic of the syndrome. Interestingly, preference for routine and repetitive language were heightened in individuals with Sotos syndrome and the repetitive behavior profile was strikingly similar to that observed in individuals with Prader\u2013Willi syndrome. These findings build upon previous research and provide further evidence of the behavioral phenotype associated with Sotos syndrome. \u00a9 2015 Wiley Periodicals, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ajmg.a.37373","type":"journal-article","created":{"date-parts":[[2015,9,29]],"date-time":"2015-09-29T14:56:34Z","timestamp":1443538594000},"page":"2945-2956","source":"Crossref","is-referenced-by-count":32,"title":["The behavioral characteristics of Sotos syndrome"],"prefix":"10.1002","volume":"167","author":[{"given":"Krupa","family":"Sheth","sequence":"first","affiliation":[{"name":"Cerebra Centre for Neurodevelopmental Disorders, School of Psychology University of Birmingham Birmingham United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joanna","family":"Moss","sequence":"additional","affiliation":[{"name":"Cerebra Centre for Neurodevelopmental Disorders, School of Psychology University of Birmingham Birmingham United Kingdom"},{"name":"Institute of Cognitive Neuroscience University College London London United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah","family":"Hyland","sequence":"additional","affiliation":[{"name":"Cerebra Centre for Neurodevelopmental Disorders, School of Psychology University of Birmingham Birmingham United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chris","family":"Stinton","sequence":"additional","affiliation":[{"name":"Cerebra Centre for Neurodevelopmental Disorders, School of Psychology University of Birmingham Birmingham United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Trevor","family":"Cole","sequence":"additional","affiliation":[{"name":"Department of Clinical Genetics Birmingham Women's Hospital Birmingham United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chris","family":"Oliver","sequence":"additional","affiliation":[{"name":"Cerebra Centre for Neurodevelopmental Disorders, School of Psychology University of Birmingham Birmingham United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2015,9,29]]},"reference":[{"key":"e_1_2_6_2_1","unstructured":"Achenbach TM.1991a. 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