{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T03:54:42Z","timestamp":1777694082380,"version":"3.51.4"},"reference-count":28,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2015,10,14]],"date-time":"2015-10-14T00:00:00Z","timestamp":1444780800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["American J of Med Genetics Pt A"],"published-print":{"date-parts":[[2016,2]]},"abstract":"<jats:sec><jats:label\/><jats:p>The aim of our study was to determine the frequency and type of associated congenital anomalies in patients with isolated gastroschisis born at the Dr. Juan I. Menchaca Civil Hospital of Guadalajara (Guadalajara, M\u00e9xico), and to explore its possible association with the included outcome variables. One hundred\u2010eight cases with isolated gastroschisis were reviewed from 2009 to 2014. The occurrence of intestinal and extraintestinal associated anomalies (either secondary or primary) was prospectively assessed. The type of gastroschisis, length of hospital stay (LOS), and in\u2010hospital mortality were outcome variables for statistical analysis. Of infants with gastroschisis, 52 (48.1%) had one or more associated anomalies (AA), with increased odds in males (OR\u2009=\u20092.3, 95%CI: 1.1\u20135.0). AA classified, as secondary and primary were present in 34.3 and 5.6% of patients, respectively. Of secondary AA, 25.9% were intestinal anomalies, and 17.6% were extraintestinal. Primary AA were congenital heart disease (n\u2009=\u20093), meningomyelocele, and hydrocephaly and amniotic band sequence in one instance, respectively. Multivariate logistic regression showed that secondary AA (both intestinal and extraintestinal) were associated with complex gastroschisis, prolonged LOS, and in\u2010hospital death, whereas primary AA were not related to a worse outcome. Our results highlight the pathogenic importance of properly investigating and categorizing the presence of others secondary or primary AA when diagnosis of gastroschisis is made. \u00a9 2015 Wiley Periodicals, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ajmg.a.37433","type":"journal-article","created":{"date-parts":[[2015,10,14]],"date-time":"2015-10-14T12:28:52Z","timestamp":1444825732000},"page":"316-321","source":"Crossref","is-referenced-by-count":6,"title":["Associated congenital anomalies in infants with isolated gastroschisis: A single\u2010institutional experience"],"prefix":"10.1002","volume":"170","author":[{"given":"Jorge Rom\u00e1n","family":"Corona\u2010Rivera","sequence":"first","affiliation":[{"name":"Center for Registry and Research in Congenital Anomalies (<i>CRIAC<\/i>) Service of Genetics and Cytogenetics Unit, Pediatrics Division, Dr. Juan I. Menchaca Civil Hospital of Guadalajara Guadalajara Jalisco M\u00e9xico"},{"name":"Department of Molecular Biology and Genomics Dr. Enrique Corona\u2010Rivera Institute of Human Genetics  Health Sciences University Center, University of Guadalajara Guadalajara Jalisco M\u00e9xico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rafael","family":"Nieto\u2010Garc\u00eda","sequence":"additional","affiliation":[{"name":"Service of Cardiology Dr. Juan I. Menchaca Civil Hospital of Guadalajara Guadalajara Jalisco M\u00e9xico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eloy","family":"L\u00f3pez\u2010Marure","sequence":"additional","affiliation":[{"name":"Service of Radiology Dr. Juan I. Menchaca Civil Hospital of Guadalajara Guadalajara Jalisco M\u00e9xico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juan Jos\u00e9","family":"C\u00e1rdenas\u2010Ruiz Velasco","sequence":"additional","affiliation":[{"name":"Service of Pediatric Surgery Dr. Juan I. Menchaca Civil Hospital of Guadalajara Guadalajara Jalisco M\u00e9xico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lucina","family":"Bobadilla\u2010Morales","sequence":"additional","affiliation":[{"name":"Center for Registry and Research in Congenital Anomalies (<i>CRIAC<\/i>) Service of Genetics and Cytogenetics Unit, Pediatrics Division, Dr. Juan I. 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