{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T01:24:09Z","timestamp":1780449849229,"version":"3.54.1"},"reference-count":40,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2016,9,12]],"date-time":"2016-09-12T00:00:00Z","timestamp":1473638400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Espersen and Luth Mehlsens"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["American J of Med Genetics Pt A"],"published-print":{"date-parts":[[2017,1]]},"abstract":"<jats:sec><jats:label\/><jats:p>The present study describes seven patients with Nance\u2013Horan syndrome, all referred to a specialized oral care unit in the Central Denmark Region. A literature search on \u201cNance Horan Syndrome\u201d resulted in 53 publications among which 29 reported on dental findings. Findings reported in these papers have been systematized to obtain an overview of the reported findings and the terminology on dental morphology. All seven patients included in the present study showed deviations of crown morphology on incisors and\/or molars. The only consistent and very clear dental aberration was alterations in the tooth morphology that is screwdriver\u2010shaped incisors and bud molars being most pronounced in the permanent dentition, but were also present in the primary dentition. In addition, three patients had supernumerary teeth, and three had dental agenesis. In conclusion, a dental examination as a part of the diagnostic process may reveal distinct characteristics of the dental morphology, which could be of diagnostic value and facilitate an early diagnosis. In the description of molar morphology in NHS patients, it is recommended to use the term \u201cbud molar.\u201d The combination of congenital cataract, screwdriwer\u2010shaped incisors and bud\u2010shaped molars is a strong clinical indication of Nance\u2013Horan syndrome. \u00a9 2016 Wiley Periodicals, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ajmg.a.37963","type":"journal-article","created":{"date-parts":[[2016,9,12]],"date-time":"2016-09-12T12:07:15Z","timestamp":1473682035000},"page":"88-98","source":"Crossref","is-referenced-by-count":24,"title":["Nance\u2013Horan syndrome\u2014The oral perspective on a rare disease"],"prefix":"10.1002","volume":"173","author":[{"given":"Hans","family":"Gj\u00f8rup","sequence":"first","affiliation":[{"name":"Section of Oral Health in Rare Diseases Department of Maxillofacial Surgery, Aarhus University Hospital Aarhus Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dorte","family":"Haubek","sequence":"additional","affiliation":[{"name":"Section for Pediatric Dentistry Department of Dentistry, Health, Aarhus University Aarhus Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pernille","family":"Jacobsen","sequence":"additional","affiliation":[{"name":"Department of Specialized Oral Health Care Viborg Regional Hospital, Central Jutland Viborg Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John R.","family":"Ostergaard","sequence":"additional","affiliation":[{"name":"Center for Rare Diseases Department of Pediatrics, Aarhus University Hospital Aarhus Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,9,12]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00431-015-2520-x"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1080\/00016350310001451"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-0004.1984.tb00783.x"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1080\/13816810490514360"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1086\/379381"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1038\/ejhg.2011.52"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/ddp206"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1080\/13816810902822021"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.ejhg.5201671"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1601-0825.1995.tb00150.x"},{"key":"e_1_2_7_12_1","unstructured":"Gene expression in tooth. 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