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Microdeletions of chromosome 13q that include the <jats:italic>MIR17HG<\/jats:italic> gene were found in all three. One of the patients was treated successfully with growth hormone. In addition to expanding the phenotype of Feingold 2 syndrome, we suggest management of patients with Feingold 2 syndrome include echocardiography at the time of diagnosis in all patients and consideration of evaluation for growth hormone deficiency in patients with short stature.<\/jats:p>","DOI":"10.1002\/ajmg.a.61037","type":"journal-article","created":{"date-parts":[[2019,1,24]],"date-time":"2019-01-24T14:48:38Z","timestamp":1548341318000},"page":"410-416","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Growth hormone deficiency, aortic dilation, and neurocognitive issues in Feingold syndrome 2"],"prefix":"10.1002","volume":"179","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0386-7622","authenticated-orcid":false,"given":"Michael","family":"Muriello","sequence":"first","affiliation":[{"name":"McKusick\u2010Nathans Institute of Genetic Medicine Johns Hopkins University  Baltimore 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