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Also, the outcome of newborns with congenital anomalies is expected to be poor, due to a lack of state\u2010of\u2010the art care. We conducted a study of 102 newborns recruited in the Neonatal Intensive Care Unit (NICU) at the University Hospitals of Kinshasa, DR Congo, to assess the impact of congenital anomalies. The presence of a major anomaly was associated with a hazard ratio of death of 13.2 (95%CI: 3.7\u201346.7, <jats:italic>p<\/jats:italic>\u2009&lt;\u2009.001). In addition, the presence of three or more minor anomalies was associated with a 4.5\u2010fold increased risk of death (95%CI: 1.1\u201318.6, <jats:italic>p<\/jats:italic> = .04). We conclude that like major anomalies, the presence of three or more minor anomalies should also be given particular attention and that the evaluation of dysmorphism should be promoted in NICU.<\/jats:p>","DOI":"10.1002\/ajmg.a.61987","type":"journal-article","created":{"date-parts":[[2020,11,28]],"date-time":"2020-11-28T06:40:02Z","timestamp":1606545602000},"page":"453-460","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Dysmorphism and major anomalies are a main predictor of survival in newborns admitted to the neonatal intensive care unit in the Democratic Republic of Congo"],"prefix":"10.1002","volume":"185","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8870-0575","authenticated-orcid":false,"given":"Gerrye","family":"Mubungu","sequence":"first","affiliation":[{"name":"Faculty of Medicine, Center for Human Genetics University of Kinshasa  Kinshasa Congo"},{"name":"Faculty of Medicine, Department of 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