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Both autosomal dominant and recessive patterns of inheritance are observed with many causative genes. Here, we present the phenotypes and genotypes of four children with RS from different Indian families. Sequence variants were identified in genes <jats:italic>ROR2<\/jats:italic>, <jats:italic>DVL1<\/jats:italic>, and <jats:italic>DVL3<\/jats:italic>. Our results expand the mutational spectrum of RS and we also highlight the radiological changes in the radius and ulna in patients with <jats:italic>ROR2<\/jats:italic> sequence variants which are primarily characteristic for <jats:italic>ROR2<\/jats:italic> related RS but have been reported in <jats:italic>WNT5A<\/jats:italic> related RS.<\/jats:p>","DOI":"10.1002\/ajmg.a.62082","type":"journal-article","created":{"date-parts":[[2021,1,26]],"date-time":"2021-01-26T08:34:19Z","timestamp":1611650059000},"page":"1105-1112","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Clinical and molecular characterization of four patients with Robinow syndrome from different families"],"prefix":"10.1002","volume":"185","author":[{"given":"Archana","family":"Rai","sequence":"first","affiliation":[{"name":"Department of Medical Genetics Sanjay Gandhi Postgraduate Institute of Medical Sciences  Lucknow India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7154-3449","authenticated-orcid":false,"given":"Siddaramappa J.","family":"Patil","sequence":"additional","affiliation":[{"name":"Division of Medical Genetics Narayana Hrudayalaya Hospitals, Mazumdar\u2010Shaw Medical Center  Bangalore India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Priyanka","family":"Srivastava","sequence":"additional","affiliation":[{"name":"Genetic Metabolic Unit, Department of Pediatrics Post Graduate Institute of Medical Education and Research  Chandigarh India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kalpana","family":"Gaurishankar","sequence":"additional","affiliation":[{"name":"Department of Medical Genetics Apollo Hospitals and Kanchi Kamakoti Childs Trust Hospital  Chennai India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6624-082X","authenticated-orcid":false,"given":"Shubha R.","family":"Phadke","sequence":"additional","affiliation":[{"name":"Department of Medical Genetics Sanjay Gandhi Postgraduate Institute of Medical Sciences  Lucknow India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,1,26]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajhg.2015.02.010"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.a.36677"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.a.38635"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1001\/archoto.2011.1459"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jclinane.2020.109752"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1177\/2324709620911771"},{"issue":"1","key":"e_1_2_10_8_1","first-page":"89","article-title":"Robinow syndrome","volume":"41","author":"Kulkarni M. 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