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There is growing evidence that molecular changes at the imprinted <jats:italic>MEST<\/jats:italic> region in 7q32.2 are associated with a phenotype evocative of SRS. This report details a patient with a SRS\u2010like phenotype and a paternally inherited microdeletion of 79 kilobases (35\u2010fold smaller than the previously reported smallest deletion) in the 7q32.2 region. This microdeletion encompasses only five genes, including <jats:italic>MEST<\/jats:italic>, which corroborates the hypothesis that <jats:italic>MEST<\/jats:italic> plays a central role in the 7q32.2 microdeletion growth disorder, as well as further implicating <jats:italic>MEST<\/jats:italic> in upd(7)mat SRS itself.<\/jats:p>","DOI":"10.1002\/ajmg.a.62782","type":"journal-article","created":{"date-parts":[[2022,5,20]],"date-time":"2022-05-20T12:25:27Z","timestamp":1653049527000},"page":"2421-2428","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["A 79\u2010kb paternally inherited 7q32.2 microdeletion involving <scp><i>MEST<\/i><\/scp> in a patient with a <scp>Silver\u2010Russell<\/scp> syndrome\u2010like phenotype"],"prefix":"10.1002","volume":"188","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4345-6094","authenticated-orcid":false,"given":"Krista 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