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This study presents the first mortality analysis associated with KID syndrome, focusing on a case report of a Latin American patient. Our aim is to establish extensive genotype\u2013phenotype correlations, particularly in relation to the causes of death. Molecular studies enable us to confirm the disease's etiology and establish the causes of death with certain pathogenic variants. This information provides healthcare professionals with valuable guidelines for management and allows for the development of appropriate therapeutic strategies.\n                  <\/jats:p>","DOI":"10.1002\/ajmg.a.64181","type":"journal-article","created":{"date-parts":[[2025,7,10]],"date-time":"2025-07-10T06:30:07Z","timestamp":1752129007000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Genotype\u2013Phenotype Correlations, Mortality, and Clinical Insights in Keratitis\u2013Ichthyosis\u2013Deafness Syndrome: A Comprehensive Review and Case Report"],"prefix":"10.1002","volume":"197","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8981-055X","authenticated-orcid":false,"given":"Leslie","family":"Patr\u00f3n\u2010Romero","sequence":"first","affiliation":[{"name":"Faculty of Medicine and Psychology Autonomous University of Baja California  Tijuana 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