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Utilizing online surveys from the Dutch Down Syndrome Foundation, the research analyzes changes in diagnostic communication, parental satisfaction, and screening considerations over time. Findings indicate a rising uptake of prenatal screening among survey respondents. Yet, they reported lower overall satisfaction with their prenatal diagnostic experience in later surveys. Notably, 39% (16\/41) of parents with a prenatal suggestive diagnosis in 2024 felt pressured to terminate the pregnancy. Values\u2010based reasons for opting out of screening, such as welcoming a child with DS, have significantly increased over time. The study highlights disparities in information adequacy and communication quality across different healthcare professionals. Findings suggest a need for improved counseling and support for parents undergoing DS screening and diagnosis, particularly in prenatal contexts.<\/jats:p>","DOI":"10.1002\/ajmg.a.64250","type":"journal-article","created":{"date-parts":[[2025,9,20]],"date-time":"2025-09-20T02:13:17Z","timestamp":1758334397000},"page":"316-328","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Parents' Experiences of Diagnosis and Screening for Down Syndrome in The Netherlands"],"prefix":"10.1002","volume":"200","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4990-5711","authenticated-orcid":false,"given":"Gert","family":"de Graaf","sequence":"first","affiliation":[{"name":"Dutch Down Syndrome Foundation  Meppel the Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5232-9882","authenticated-orcid":false,"given":"Brian G.","family":"Skotko","sequence":"additional","affiliation":[{"name":"Down Syndrome Program, Division of Medical Genetics and Metabolism, Department of Pediatrics Massachusetts General Hospital  Boston Massachusetts USA"},{"name":"Department of Pediatrics Harvard Medical School  Boston Massachusetts USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,9,19]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.a.63619"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.a.63981"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1177\/0049124113500475"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-7610.1988.tb00734.x"},{"key":"e_1_2_10_6_1","unstructured":"CBS.2025.Tabel Bevolking; Hoogstbehaald Onderwijsniveau en Onderwijsrichting. 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