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(2006); Hum Mol Genet 15:2170\u20132182]. We genotyped these six SNPs in 1,212 unrelated Caucasian patients of UK origin with LOAD and 1,389 ethnically, gender and age matched control subjects. We did not observe a statistically significant association with the risk of LOAD for any of the six SNPs in the sample as a whole. When stratifying the sample by APOE one SNP (intergenic SNP rs11190302) was associated with LOAD in individuals lacking the <jats:italic>\u03b54<\/jats:italic> allele (genotypic <jats:italic>P<\/jats:italic>\u2009=\u20090.027, allelic <jats:italic>P<\/jats:italic>\u2009=\u20090.066). However this association was in the opposite direction to that detected in the Japanese population. It remains to be determined whether <jats:italic>DNMBP<\/jats:italic> is associated with LOAD. \u00a9 2008 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/ajmg.b.30768","type":"journal-article","created":{"date-parts":[[2008,5,1]],"date-time":"2008-05-01T18:27:43Z","timestamp":1209666463000},"page":"61-64","source":"Crossref","is-referenced-by-count":2,"title":["Association analysis of dynamin\u2010binding protein (<i>DNMBP<\/i>) on chromosome 10q with late onset Alzheimer's disease in a large caucasian UK 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