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We found evidence for a major dyslexia locus on chromosome 6p21. The cognitive trait rapid naming (objects\/colors) produced a genome\u2010wide significant LOD score of 5.87 (<jats:italic>P<\/jats:italic>\u2009=\u20091.00\u2009\u00d7\u200910<jats:sup>\u22127<\/jats:sup>) and the implicated 6p\u2010risk region spans around 10\u2009Mb. Although our finding maps close to DYX2, where the dyslexia candidate genes <jats:italic>DCDC2<\/jats:italic> and <jats:italic>KIAA0319<\/jats:italic> have already been identified, our data point to the presence of an additional risk gene in this region and are highlighting the impact of 6p21 in dyslexia and related cognitive traits. \u00a9 2010 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/ajmg.b.31135","type":"journal-article","created":{"date-parts":[[2010,11,3]],"date-time":"2010-11-03T04:50:27Z","timestamp":1288759827000},"page":"36-43","source":"Crossref","is-referenced-by-count":24,"title":["Mapping for dyslexia and related cognitive trait loci provides strong evidence for further risk genes on chromosome 6p21"],"prefix":"10.1002","volume":"156","author":[{"given":"Inke 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