{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T02:59:42Z","timestamp":1773284382833,"version":"3.50.1"},"reference-count":33,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2015,8,18]],"date-time":"2015-08-18T00:00:00Z","timestamp":1439856000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"NWO\/MaGW VIDI","award":["016-065-318"],"award-info":[{"award-number":["016-065-318"]}]},{"name":"Science Policy Unit Valenc\u00eda","award":["BEFPI\/2014\/017"],"award-info":[{"award-number":["BEFPI\/2014\/017"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["American J of Med Genetics Pt B"],"published-print":{"date-parts":[[2016,12]]},"abstract":"<jats:sec><jats:label\/><jats:p>Autistic traits are characterized by social and communication problems, restricted, repetitive and stereotyped patterns of behavior, interests and activities. The relation between autistic traits and personality characteristics is largely unknown. This study focused on the relation between five specific autistic traits measured with the abridged version of the Autism Spectrum Quotient (\u201csocial problems,\u201d \u201cpreference for routine,\u201d \u201cattentional switching difficulties,\u201d \u201cimagination impairments,\u201d \u201cfascination for numbers and patterns\u201d) and Experience Seeking (ES) in a general population sample of adults, and subsequently investigated the genetic and environmental etiology between these traits. Self\u2010reported data on autistic traits and ES were collected in a population sample (n\u2009=\u2009559) of unrelated individuals, and in a population based family sample of twins and siblings (n\u2009=\u2009560). Phenotypic, genetic and environmental associations between traits were examined in a bivariate model, accounting for sex and age differences. Phenotypically, ES correlated significantly with \u201cpreference for routine\u201d and \u201cimagination impairments\u201d in both samples but was unrelated to the other autistic traits. Genetic analyses in the family sample revealed that the association between ES and \u201cpreference for routine\u201d and \u201cimagination impairments\u201d could largely be explained by a shared genetic factor (89% and 70%, respectively). Our analyses demonstrated at a phenotypic and genetic level an inverse relationship between ES and specific autistic traits in adults. ES is associated with risk taking behavior such as substance abuse, antisocial behavior and financial problems. Future research could investigate whether autistic traits, in particular strong routine preference and impaired imagination skills, serve as protective factors for such risky behaviors. \u00a9 2015 Wiley Periodicals, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ajmg.b.32352","type":"journal-article","created":{"date-parts":[[2015,8,18]],"date-time":"2015-08-18T16:55:27Z","timestamp":1439916927000},"page":"1190-1197","source":"Crossref","is-referenced-by-count":5,"title":["Genetic and environmental contributions to the inverse association between specific autistic traits and experience seeking in adults"],"prefix":"10.1002","volume":"171","author":[{"given":"\u00c1ngel","family":"Romero\u2010Mart\u00ednez","sequence":"first","affiliation":[{"name":"Department of Psychobiology University of Valencia Valencia Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lu\u00eds","family":"Moya\u2010Albiol","sequence":"additional","affiliation":[{"name":"Department of Psychobiology University of Valencia Valencia Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anna A. 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