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PD is a common mental disorder, characterized by recurring and unprovoked panic attacks, and genetic factors have been estimated to explain around 40% of the risk. In this study the potential enrichment of PD risk variants was explored based on whole\u2010exome sequencing of 54 patients with PD and 211 control individuals from the Faroese population. No genome\u2010wide significant associations were found, however several single variants and genes showed strong association with PD, where<jats:italic>DGKH<\/jats:italic>was found to be the strongest PD associated gene. Interestingly<jats:italic>DGKH<\/jats:italic>has previously demonstrated genome\u2010wide significant association with bipolar disorder as well as evidence of association to other mental disorders. Additionally, we found an enrichment of PD risk variants in the Faroese population; variants with otherwise low frequency in more outbreed European populations. \u00a9 2016 Wiley Periodicals, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ajmg.b.32464","type":"journal-article","created":{"date-parts":[[2016,6,3]],"date-time":"2016-06-03T05:12:56Z","timestamp":1464930776000},"page":"1013-1022","source":"Crossref","is-referenced-by-count":22,"title":["Whole\u2010exome sequencing implicates<i>DGKH<\/i>as a risk gene for panic disorder in the Faroese population"],"prefix":"10.1002","volume":"171","author":[{"given":"Noomi O.","family":"Gregersen","sequence":"first","affiliation":[{"name":"Translational Neuropsychiatry Unit Department of Clinical Medicine Aarhus University Aarhus Denmark"},{"name":"Department of Biomedicine and Centre for Integrative Sequencing iSEQ Aarhus University Aarhus Denmark"},{"name":"The Lundbeck Foundation Initiative for Integrative Psychiatric Research 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