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These findings might lead to better support for 22q11DS maternal mental health. An international sample of 71 mothers (<jats:italic>M<\/jats:italic>\u2009=\u200940.5\u2009years) of children with 22q11DS (<jats:italic>M<\/jats:italic>\u2009=\u20099.2\u2009years) was recruited and completed an online survey assessing maternal mental health (symptoms of depression, anxiety, traumatic stress, general stress, and alcohol consumption), coping methods, and mental health protective factors (social support, dyadic adjustment, parenting competence). Maternal ratings of child mental health symptoms were also obtained. Mothers' self\u2010report revealed a high percentage who screened positive for elevated levels of general stress (69%), hazardous alcohol consumption (30.9%), traumatic stress (33.8%), anxiety (26.8%), and depression (26.8%). After controlling for demographic variables and child mental health symptoms, maternal self\u2010reported maladaptive coping methods were positively associated with maternal symptoms of depression, anxiety, stress, and traumatic stress. Reducing maladaptive coping methods may be a promising intervention for improving mental health in mothers of children with 22q11DS.<\/jats:p>","DOI":"10.1002\/ajmg.b.32973","type":"journal-article","created":{"date-parts":[[2024,2,27]],"date-time":"2024-02-27T07:34:48Z","timestamp":1709019288000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Mental health, coping, and protective factors in mothers of children with 22q11.2 deletion syndrome"],"prefix":"10.1002","volume":"195","author":[{"ORCID":"https:\/\/orcid.org\/0009-0004-3085-3052","authenticated-orcid":false,"given":"Haley","family":"McBride","sequence":"first","affiliation":[{"name":"Department of Psychology Syracuse University  Syracuse New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nandini","family":"Jhawar","sequence":"additional","affiliation":[{"name":"Department of Psychology Syracuse University  Syracuse New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laurie","family":"Boucicaut","sequence":"additional","affiliation":[{"name":"Department of Psychology Syracuse University  Syracuse New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carrie E.","family":"Bearden","sequence":"additional","affiliation":[{"name":"Department of Psychiatry and Biobehavioral Sciences and Psychology UCLA Semel Institute for Neuroscience and Human Behavior  Los Angeles California USA"},{"name":"Department of Psychology UCLA Semel Institute for Neuroscience and Human Behavior  Los Angeles California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wendy R.","family":"Kates","sequence":"additional","affiliation":[{"name":"Department of Psychiatry and Behavioral Sciences SUNY\u2010Upstate Medical University  Syracuse New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah E.","family":"Woolf\u2010King","sequence":"additional","affiliation":[{"name":"Department of Psychology Syracuse University  Syracuse New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kevin M.","family":"Antshel","sequence":"additional","affiliation":[{"name":"Department of Psychology Syracuse University  Syracuse New York USA"},{"name":"Department of Psychiatry and Behavioral Sciences SUNY\u2010Upstate Medical University  Syracuse New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,2,26]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/cch.12457"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/ddrr.7"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/mpr.329"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rasd.2009.09.008"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10803-011-1198-9"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph18052707"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2214.2008.00850.x"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.158.16.1789"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1207\/s15327558ijbm0401_6"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jad.2020.01.084"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.2307\/2136404"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12687-021-00558-9"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1037\/ser0000089"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2018-3259"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cpr.2004.02.002"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.a.40387"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1097\/chi.0b013e318032384b"},{"key":"e_1_2_10_19_1","first-page":"225","article-title":"The PSC\u201017: A brief pediatric symptom checklist with psychosocial problem subscales. 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