{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,29]],"date-time":"2025-08-29T10:11:09Z","timestamp":1756462269784},"reference-count":64,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2004,10,5]],"date-time":"2004-10-05T00:00:00Z","timestamp":1096934400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["American J of Med Genetics Pt C"],"published-print":{"date-parts":[[2004,11,15]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Hair and nail development have many similarities and are likely to share many developmental pathways. This is evident from the ectodermal dysplasias that affect both appendages. Of special interest are syndromic disorders as they show the effects of disturbances in molecular pathways that are essential for normal embryonic development. In this review, recent results from studies of syndrome affecting hair and nail development will be discussed. \u00a9 2004 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/ajmg.c.30034","type":"journal-article","created":{"date-parts":[[2004,10,5]],"date-time":"2004-10-05T22:01:20Z","timestamp":1097013680000},"page":"52-60","source":"Crossref","is-referenced-by-count":4,"title":["Molecular genetics of hereditary hair and nail disease"],"prefix":"10.1002","volume":"131C","author":[{"given":"M.A.M.","family":"van Steensel","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"van Geel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.M.","family":"Steijlen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2004,10,5]]},"reference":[{"key":"e_1_2_3_2_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.279.5351.720"},{"key":"e_1_2_3_3_1","doi-asserted-by":"publisher","DOI":"10.1086\/302069"},{"key":"e_1_2_3_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/eji.1830220626"},{"issue":"7","key":"e_1_2_3_5_1","first-page":"937","article-title":"Interactions between dorsal\u2010ventral patterning genes lmx1b, engrailed\u20101, and wnt\u20107a in the vertebrate limb","volume":"46","author":"Chen H","year":"2002","journal-title":"Int J Dev Biol"},{"key":"e_1_2_3_6_1","doi-asserted-by":"publisher","DOI":"10.1242\/dev.122.10.3035"},{"key":"e_1_2_3_7_1","doi-asserted-by":"publisher","DOI":"10.1242\/dev.124.24.5021"},{"key":"e_1_2_3_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1521-1878(200001)22:1<72::AID-BIES12>3.0.CO;2-S"},{"key":"e_1_2_3_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-4644(1999)75:32 <141::AID-JCB17>3.0.CO;2-A"},{"key":"e_1_2_3_10_1","doi-asserted-by":"publisher","DOI":"10.1080\/000155500750042853"},{"key":"e_1_2_3_11_1","doi-asserted-by":"publisher","DOI":"10.1038\/ng0695-202"},{"key":"e_1_2_3_12_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.273.5279.1236"},{"issue":"6","key":"e_1_2_3_13_1","first-page":"515","article-title":"Hypotrichosis, lymphedema of the legs and acral telangiectasias\u2014New syndrome?","volume":"11","author":"Glade C","year":"2001","journal-title":"Eur J Dermatol"},{"key":"e_1_2_3_14_1","doi-asserted-by":"publisher","DOI":"10.1136\/jmg.37.2.81"},{"key":"e_1_2_3_15_1","doi-asserted-by":"publisher","DOI":"10.1038\/35043032"},{"key":"e_1_2_3_16_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.273.35.22640"},{"key":"e_1_2_3_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/0168-9525(92)90350-D"},{"key":"e_1_2_3_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0092-8674(00)80562-0"},{"key":"e_1_2_3_19_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2133.1999.03038.x"},{"key":"e_1_2_3_20_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M308512200"},{"key":"e_1_2_3_21_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M304886200"},{"key":"e_1_2_3_22_1","doi-asserted-by":"publisher","DOI":"10.1086\/375614"},{"key":"e_1_2_3_23_1","doi-asserted-by":"publisher","DOI":"10.1038\/ncb0402-e101"},{"key":"e_1_2_3_24_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature01458"},{"key":"e_1_2_3_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0733-8635(05)70390-9"},{"key":"e_1_2_3_26_1","doi-asserted-by":"publisher","DOI":"10.1086\/321271"},{"key":"e_1_2_3_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/0065-2571(94)90014-0"},{"key":"e_1_2_3_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0092-8674(03)00273-3"},{"key":"e_1_2_3_29_1","doi-asserted-by":"publisher","DOI":"10.1038\/79851"},{"key":"e_1_2_3_30_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M103305200"},{"key":"e_1_2_3_31_1","doi-asserted-by":"publisher","DOI":"10.1038\/ng1163"},{"key":"e_1_2_3_32_1","doi-asserted-by":"publisher","DOI":"10.1038\/382360a0"},{"key":"e_1_2_3_33_1","doi-asserted-by":"publisher","DOI":"10.1242\/dev.125.6.1137"},{"key":"e_1_2_3_34_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00275189"},{"key":"e_1_2_3_35_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1965.03080090029007"},{"key":"e_1_2_3_36_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2230.2001.00819.x"},{"key":"e_1_2_3_37_1","doi-asserted-by":"publisher","DOI":"10.1038\/ng1097-240"},{"key":"e_1_2_3_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(00)02379-5"},{"key":"e_1_2_3_39_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.0022-202x.2001.01438.x"},{"key":"e_1_2_3_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0960-9822(99)80018-9"},{"key":"e_1_2_3_41_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9440(10)65110-3"},{"key":"e_1_2_3_42_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9440(10)64621-4"},{"key":"e_1_2_3_43_1","doi-asserted-by":"publisher","DOI":"10.1101\/gad.916701"},{"key":"e_1_2_3_44_1","doi-asserted-by":"publisher","DOI":"10.1210\/me.2002-0115"},{"key":"e_1_2_3_45_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0960-9822(00)00510-8"},{"key":"e_1_2_3_46_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0925-4773(98)00177-4"},{"key":"e_1_2_3_47_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1991.tb00423.x"},{"key":"e_1_2_3_48_1","doi-asserted-by":"publisher","DOI":"10.1086\/339986"},{"key":"e_1_2_3_49_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.a.20443"},{"key":"e_1_2_3_50_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M100201200"},{"key":"e_1_2_3_51_1","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/11.20.2371"},{"issue":"11","key":"e_1_2_3_52_1","first-page":"1955","article-title":"Interaction of intracellular proteases and immune mechanisms","volume":"36","author":"Stefanovic J","year":"1977","journal-title":"Acta Biol Med Ger"},{"key":"e_1_2_3_53_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.0022-202X.2003.22302.x"},{"key":"e_1_2_3_54_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2133.1996.31794.x"},{"key":"e_1_2_3_55_1","doi-asserted-by":"publisher","DOI":"10.1136\/jmg.40.3.153"},{"key":"e_1_2_3_56_1","doi-asserted-by":"publisher","DOI":"10.1038\/70525"},{"key":"e_1_2_3_57_1","doi-asserted-by":"publisher","DOI":"10.1038\/74155"},{"key":"e_1_2_3_58_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2133.2002.04893.x"},{"key":"e_1_2_3_59_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1523-1747.2002.01735.x"},{"key":"e_1_2_3_60_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2133.2002.04840.x"},{"key":"e_1_2_3_61_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.0022-202X.2004.23204.x"},{"key":"e_1_2_3_62_1","doi-asserted-by":"publisher","DOI":"10.1038\/ng0896-417"},{"key":"e_1_2_3_63_1","doi-asserted-by":"publisher","DOI":"10.1007\/s004390050607"},{"key":"e_1_2_3_64_1","doi-asserted-by":"publisher","DOI":"10.1038\/ng0897-372"},{"key":"e_1_2_3_65_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1097-2765(00)80200-2"}],"container-title":["American Journal of Medical Genetics Part C: Seminars in Medical Genetics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fajmg.c.30034","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ajmg.c.30034","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,13]],"date-time":"2023-09-13T10:19:35Z","timestamp":1694600375000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ajmg.c.30034"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,10,5]]},"references-count":64,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2004,11,15]]}},"alternative-id":["10.1002\/ajmg.c.30034"],"URL":"https:\/\/doi.org\/10.1002\/ajmg.c.30034","archive":["Portico"],"relation":{},"ISSN":["1552-4868","1552-4876"],"issn-type":[{"value":"1552-4868","type":"print"},{"value":"1552-4876","type":"electronic"}],"subject":[],"published":{"date-parts":[[2004,10,5]]}}}