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Almost all cases are diagnosed prenatally using midtrimester ultrasound and maternal serum alphafetoprotein measurement. This allows most infants to be delivered in a tertiary care facility where the best mode of delivery and neonatal management can be determined. About 10% of infants with gastroschisis will have other malformations. Half of these are considered related to the gastroschisis (intestinal atresia or stenosis, malrotation, cryptorchidism, amyoplasia, urinary tract obstruction). Other associated malformations occur which are not recognized to be secondary to the gastroschisis. Prominent among these are cardiac and limb defects. Fetal and neonatal mortality are increased, but neither appear related to lethal malformations. \u00a9 2008 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/ajmg.c.30178","type":"journal-article","created":{"date-parts":[[2008,7,25]],"date-time":"2008-07-25T05:05:32Z","timestamp":1216962332000},"page":"219-230","source":"Crossref","is-referenced-by-count":34,"title":["Gastroschisis: Clinical presentation and associations"],"prefix":"10.1002","volume":"148C","author":[{"given":"Alasdair G.W.","family":"Hunter","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roger 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