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The objectives of this study were to determine the incidence of depression in an international population of adults with AMC and to identify variables independently associated with depression. This cross\u2010sectional study used independent samples <jats:italic>t<\/jats:italic>\u2010test and hierarchical multiple regression. The mean Hospital Anxiety and Depression Scale\u2014depression (HADS\u2010D) score of our sample, which included 60 adults with AMC, was 4.0\u2009\u00b1\u20093.6, with 19% having some signs of depression. Occupation status, age, sex, physical independence, environmental factors, anxiety, and fatigue explained 52.2% of the variance in HADS\u2010D. The prevalence of depression in an adult sample of individuals with AMC is similar to that of the general adult population in the United States. 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