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To meet this assumption, we rely on the National Research Council's (NRC's) nutritional recommendations for nonhuman primates to provide accurate guidance for proper dietary formulations. We also rely on feed manufacturers to follow these guidelines. With that in mind, the purpose of this commentary is to discuss three related points that we believe have significant ramifications for the health and well being of captive primates as well as for their effective use in biomedical research. First, our laboratory has shown that most experimental primates are likely in a state of hypervitaminosis A. Second, it is apparent that many primate diets are providing vitamin A at levels higher than the NRC's recommendation. Third, the recommendation itself is based on inadequate information about nutrient needs and is likely too high, especially when compared with human requirements. Am. J. Primatol. 71:813\u2013816, 2009. \u00a9 2009 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/ajp.20714","type":"journal-article","created":{"date-parts":[[2009,8,20]],"date-time":"2009-08-20T15:06:51Z","timestamp":1250780811000},"page":"813-816","source":"Crossref","is-referenced-by-count":3,"title":["Hypervitaminosis A in experimental nonhuman primates: evidence, causes, and the road to recovery"],"prefix":"10.1002","volume":"71","author":[{"given":"Joseph T.","family":"Dever","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sherry A.","family":"Tanumihardjo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2009,5,29]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/jn\/132.12.3616"},{"key":"e_1_2_1_3_1","first-page":"CD007176","article-title":"Antioxidant supplements for prevention of mortality in healthy 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