{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,23]],"date-time":"2026-07-23T18:22:12Z","timestamp":1784830932080,"version":"3.55.0"},"reference-count":14,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2023,2,10]],"date-time":"2023-02-10T00:00:00Z","timestamp":1675987200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000208","name":"Institute of Museum and Library Services","doi-asserted-by":"publisher","award":["MG\u201030\u201015\u20100035\u201015"],"award-info":[{"award-number":["MG\u201030\u201015\u20100035\u201015"]}],"id":[{"id":"10.13039\/100000208","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000208","name":"Institute of Museum and Library Services","doi-asserted-by":"publisher","award":["MG\u201080\u201019\u20100008\u201019"],"award-info":[{"award-number":["MG\u201080\u201019\u20100008\u201019"]}],"id":[{"id":"10.13039\/100000208","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["American J Primatol"],"published-print":{"date-parts":[[2023,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>In response to the growing evidence that hypertension may play a significant role in the development of cardiovascular disease (CVD) in bonobos, the Great Ape Heart Project\u00a0established a finger blood pressure (BP) monitoring protocol for zoo\u2010housed bonobos. The ability to monitor BP without the use of anesthesia provides more opportunities to detect potential hypertension in its early stages allowing for therapeutic intervention that may slow the progression of CVD. No BP reference ranges exist for bonobos due to the lack of an established protocol, the difficulty of measuring BP in animals, and small sample size of zoo\u2010housed bonobos. By working with all 8 institutions in North America that care for bonobos, it was possible to (1) investigate the feasibility of using finger BP devices, and (2) establish BP trends for male and female bonobos. Data were collected from May 2016 to March 2019. Zoos were asked to train for and collect BP measurements from any bonobos willing to participate, regardless of age, sex, or health status as well as to report on the quality of the training and measurements obtained. At the start of the study, the North American bonobo population consisted of 74 bonobos ages 5 years and older at 8 institutions. All 8 institutions submitted at total of 3656 BP readings from 50 bonobos (<jats:italic>n<\/jats:italic>\u2009=\u200923 females, <jats:italic>n<\/jats:italic>\u2009=\u200927 males; ages 5\u221251 years) representing 67.57% of the trainable population ages 5 years and older. Of the readings submitted, 2845 were determined to be good quality, reliable BP readings (77.81% useful BP measurements) for 36 of the 50 adult bonobos submitted for this study (59.01% of the adult population ages 10\u221251 years) but showed limitations in the protocol for the younger population. BP trend analysis showed significant differences between bonobos that were not on medication versus those treated with cardiac medications, with those on cardiac mediations having significantly higher systolic arterial pressure, diastolic arterial pressure, and mean arterial pressure\u00a0(<jats:italic>p\u2009\u2264<\/jats:italic>\u20090.001 for all comparisons). Systolic BP generally increased over age classes (10\u221219, 20\u221229, 30\u221239, 40+ years).<\/jats:p>","DOI":"10.1002\/ajp.23474","type":"journal-article","created":{"date-parts":[[2023,2,10]],"date-time":"2023-02-10T08:41:23Z","timestamp":1676018483000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Blood pressure monitoring in zoologically managed bonobos (<i>Pan paniscus<\/i>)"],"prefix":"10.1002","volume":"85","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9021-0719","authenticated-orcid":false,"given":"Marietta D.","family":"Danforth","sequence":"first","affiliation":[{"name":"Great Ape Heart Project Detroit Zoological Society Royal Oak Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Victoria L.","family":"Clyde","sequence":"additional","affiliation":[{"name":"Milwaukee County Zoo  Milwaukee Wisconsin USA"},{"name":"Great Ape Heart Project Detroit Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Balbine","family":"Jourdan","sequence":"additional","affiliation":[{"name":"Veterinary Initiative for Endangered Wildlife  Bozeman Montana USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert","family":"Korman","sequence":"additional","affiliation":[{"name":"Minnesota Zoo Apple Valley Minnesota USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leann","family":"Beehler","sequence":"additional","affiliation":[{"name":"Great Ape Heart Project Detroit Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samuel","family":"Wann","sequence":"additional","affiliation":[{"name":"Great Ape Heart Project Detroit Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Priya","family":"Bapodra","sequence":"additional","affiliation":[{"name":"Columbus Zoo and Aquarium Great Ape Heart Project  Powell Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hayley","family":"Murphy","sequence":"additional","affiliation":[{"name":"Great Ape Heart Project Detroit Zoological Society Royal Oak Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Trevor","family":"Gerlach","sequence":"additional","affiliation":[{"name":"Great Ape Heart Project Detroit Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sabina","family":"Rich","sequence":"additional","affiliation":[{"name":"Department of Biomathematics North Carolina State University  Raleigh North Carolina USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abigail M.","family":"Thorgerson","sequence":"additional","affiliation":[{"name":"Center for Advancing Population Science (CAPS) Medical College of Wisconsin  Milwaukee Wisconsin USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,2,10]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1638\/2020-0022"},{"key":"e_1_2_10_3_1","volume-title":"Defining, establishing, and verifying reference intervals in the clinical laboratory: approved guideline\u2014third edition. CLSI Document C28\u2010A3","author":"CLSI","year":"2008"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/nm1095-1009"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/zoo.21044"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(15)01225-8"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1093\/ajh\/hpz118"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1177\/0300985815612154"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/B978-1-4377-1986-4.00053-6"},{"issue":"2","key":"e_1_2_10_10_1","first-page":"262","article-title":"Chronic hypertension with subsequent congestive heart failure in a western lowland gorilla (Gorilla gorilla gorilla)","volume":"30","author":"Miller C. L.","year":"1999","journal-title":"Journal of Zoo and Wildlife Medicine: Official Publication of the American Association of Zoo Veterinarians"},{"key":"e_1_2_10_11_1","first-page":"581","volume-title":"Fowler's zoo and wild animal medicine current therapy","author":"Murphy H. W.","year":"2018"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/izy.12180"},{"key":"e_1_2_10_13_1","unstructured":"Rivera S. Carrigan J. &Murphy H.(2011). Measurement of blood pressure in awake western lowland gorillas (Gorilla gorillagorilla) (abstract). Paper presented at the\u00a0American Association\u00a0of\u00a0Zoo Veterinarians."},{"key":"e_1_2_10_14_1","unstructured":"Strong V. Clyde V. Stevens J. Baiker K. Pereboom Z. Redrobe S. &White K.(submitted). A retrospective review of bonobo (Pan paniscus) mortality in European and North American Zoological collections between 2004 and 2014."},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.2146\/news170048"}],"container-title":["American Journal of Primatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ajp.23474","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/ajp.23474","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ajp.23474","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,19]],"date-time":"2023-08-19T00:57:02Z","timestamp":1692406622000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ajp.23474"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,2,10]]},"references-count":14,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2023,3]]}},"alternative-id":["10.1002\/ajp.23474"],"URL":"https:\/\/doi.org\/10.1002\/ajp.23474","archive":["Portico"],"relation":{},"ISSN":["0275-2565","1098-2345"],"issn-type":[{"value":"0275-2565","type":"print"},{"value":"1098-2345","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,2,10]]},"assertion":[{"value":"2022-07-13","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-01-14","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-02-10","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e23474"}}