{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T20:04:32Z","timestamp":1790625872214,"version":"4.1.0"},"reference-count":41,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2024,11,24]],"date-time":"2024-11-24T00:00:00Z","timestamp":1732406400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["American J Primatol"],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p>Helminthic infections, particularly those caused by trematodes, pose a significant health risk to both animals and humans. This study investigates hepatobiliary platynosomosis (HP) caused by <jats:italic>Platynosomum illiciens<\/jats:italic> in black\u2010tufted marmosets (<jats:italic>Callithrix penicillata<\/jats:italic>) in Central Brazil. Data were retrospectively collected from autopsy records at the Laboratory of Veterinary Pathology and Forensics, University of Bras\u00edlia, from January 2006 to July 2021. Epidemiological, clinical, and pathological information was analyzed, including comparisons between free\u2010ranging and captive marmosets. A total of 1596 nonhuman primate (NHP) death records were examined, with black\u2010tufted marmosets accounting for 75.6% (1206\/1595) of autopsies. HP was identified in 10.8% (131\/1206) of these cases. Captive marmosets showed a higher prevalence of HP (49.6%) than free\u2010ranging ones (6.5%). This study revealed a significant seasonal trend, with higher HP prevalence observed during the wet season until the onset of the dry season. Pathological examinations revealed severe liver and bile duct damage in fatal HP cases, including fibrosis, bile duct thickening, and the presence of flukes. Captive marmosets exhibited pronounced clinical signs, such as weight loss and apathy. Morphological and molecular analysis of sampled flukes confirmed <jats:italic>P. illiciens<\/jats:italic> infecting the marmosets. These findings underscore the substantial impact of HP on marmoset populations, particularly in captive settings. The high lethality (58% overall; 81.6% in captivity) highlights the need for improved management and preventive measures in captive environments. This study contributes to understanding HP epidemiology, clinical manifestations, and pathological outcomes, underscoring the disease's significance for the health of both free\u2010ranging and captive NHP populations. Our findings also support the need to develop targeted strategies to mitigate the impact of HP on primate species populations.<\/jats:p>","DOI":"10.1002\/ajp.23701","type":"journal-article","created":{"date-parts":[[2024,11,24]],"date-time":"2024-11-24T07:53:25Z","timestamp":1732434805000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Hepatobiliary Platynosomosis in Black\u2010Tufted Marmosets (<i>Callithrix penicillata<\/i>): A Lethal Threat for Wildlife and Captive Populations"],"prefix":"10.1002","volume":"87","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7327-9143","authenticated-orcid":false,"given":"Isabel Luana","family":"de Mac\u00eado","sequence":"first","affiliation":[{"name":"Laboratory of Veterinary Pathology and Forensic, College of Agronomy and Veterinary Medicine University of Bras\u00edlia Bras\u00edlia DF Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Davi Emanuel 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