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The right side molars were removed by dissection and caliper measured. The distal cusps of the third primary molars were sectioned, dehydrated, and embedded in Bio\u2010plastic. A slow speed diamond saw was used to section the plastic blocks and the embedded teeth. Subsequent grinding and polishing produced high quality 75 \u03bcm sections of the lamb molar cusps. No significant differences in tooth size or enamel thickness existed. Microscopic examinations show that parts of the cretin enamel were poorly calcified, an observation that was correlated to the intrauterine thyroidectomies. The data suggest that hypothyroidism alters ameloblastic activity during the secretory phase of enamel formation.<\/jats:p>","DOI":"10.1002\/ajpa.1330500309","type":"journal-article","created":{"date-parts":[[2005,8,9]],"date-time":"2005-08-09T08:22:37Z","timestamp":1123575757000},"page":"357-362","source":"Crossref","is-referenced-by-count":2,"title":["The effects of induced prenatal hypothyroidism on lamb mandibular third primary molars"],"prefix":"10.1002","volume":"50","author":[{"given":"Robert H.","family":"Biggerstaff","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jerome C.","family":"Rose","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,6,2]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1177\/00220345660450033901"},{"key":"e_1_2_1_3_1","first-page":"193","article-title":"Variations in the mineral content of Polynesian teeth","volume":"22","author":"Baume L. 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A twin study of the permanent anterior teeth","volume":"10","author":"Osborne R.","year":"1958","journal-title":"Am. J. Human Genet."},{"key":"e_1_2_1_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajpa.1330460309"},{"key":"e_1_2_1_17_1","first-page":"1946","article-title":"The neonatal line in the enamel and dentin of the human deciduous and first permanent molar","volume":"23","author":"Schour I.","year":"1936","journal-title":"J. Am. Den. Assn."},{"key":"e_1_2_1_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajpa.1330140216"},{"key":"e_1_2_1_19_1","first-page":"559","article-title":"Post\u2010mortem microscopic defects in the teeth of ancient man","volume":"59","author":"Sognnaes R. F.","year":"1955","journal-title":"Arch. Path."},{"key":"e_1_2_1_20_1","first-page":"547","article-title":"Histologic evidence of developmental lesions originating from paleolithic, prehistoric and ancient man","volume":"32","author":"Sognnaes R. F.","year":"1956","journal-title":"Am. 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