{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T21:58:12Z","timestamp":1790373492505,"version":"4.1.0"},"reference-count":60,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2005,6,3]],"date-time":"2005-06-03T00:00:00Z","timestamp":1117756800000},"content-version":"vor","delay-in-days":7154,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["American J Phys Anthropol"],"published-print":{"date-parts":[[1985,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Microcephaly is a severe developmental abnormality which is induced either genetically or environmentally. The archaeological evidence for the occurrence of this abnormality is minimal. Out of six possible cases, only three have been published; all are adult and represented solely by cranial remains. The focus of the current study is the nearly complete skeleton of a 3\u2010year\u2010old child recovered during archaeological excavations in San Jose, California. The individual is compared to a sample of 184 California Indians, ranging from 0.5 to 5 years, which were also recovered from archaeological excavations. In order to determine if microcephaly was the only disorder represented, metrical comparisons of the skull and postcrania and gross mor\u2010phological comparisons of endocranial casts were made. Based on these comparisons the individual was determined to have a cranial vault size comparable to 6\u2010month\u2010old infants (630 cc), a facial skeleton equivalent to the 9\u2010month\u2010old to 2\u2010year\u2010old age groups, and a reduced stature. Due to the mosaic nature of the skull, the observed morphology was interpreted in terms of functional cranial components. Severe malformation of the orbital aspect of the frontal lobes was found in conjunction with a significant reduction in size of the cerebral cortex and left temporal lobe. On the basis of this analysis, the individual was found to exhibit the total morphological pattern associated with microcephaly: A differential diagnosis of other possible genetic disorders is also presented.<\/jats:p>","DOI":"10.1002\/ajpa.1330680305","type":"journal-article","created":{"date-parts":[[2006,2,3]],"date-time":"2006-02-03T20:58:07Z","timestamp":1139000287000},"page":"343-357","source":"Crossref","is-referenced-by-count":17,"title":["Analysis of a microcephalic child from the late period (ca. 1100\u20131700 A.D.) of Central California"],"prefix":"10.1002","volume":"68","author":[{"given":"Gary D.","family":"Richards","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2005,6,3]]},"reference":[{"key":"e_1_2_1_2_1","first-page":"151","volume-title":"Advances in World Archaeology","author":"Akazawa T","year":"1982"},{"key":"e_1_2_1_3_1","first-page":"482","volume":"12","author":"Baillarger J","year":"1857","journal-title":"Gazaette Medicale de Paris"},{"key":"e_1_2_1_4_1","volume-title":"Human Osteology","author":"Bass WM","year":"1971"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1176\/ajp.97.5.1135"},{"key":"e_1_2_1_6_1","first-page":"637","article-title":"A clinical and genetical study of microcephaly","volume":"57","author":"B\u00f6\u00f6k JA","year":"1953","journal-title":"Amer. J. Ment. Defic."},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/aja.1000680204"},{"key":"e_1_2_1_8_1","volume-title":"Digging Up Bones","author":"Brothwell DR","year":"1981"},{"key":"e_1_2_1_9_1","doi-asserted-by":"publisher","DOI":"10.2307\/2843909"},{"key":"e_1_2_1_10_1","unstructured":"Clewlow CW (1981) Task III Report for SC1\u2013124.On file at the Society for California Archaeology District Clearinghouse #5."},{"key":"e_1_2_1_11_1","volume-title":"External Morphology of the Primate Brain","author":"Connolly CJ","year":"1950"},{"key":"e_1_2_1_12_1","first-page":"42","article-title":"The genetics and sub\u2013classification of microcephaly","volume":"1","author":"Cowie V","year":"1960","journal-title":"J. Ment. Defic. Res."},{"key":"e_1_2_1_13_1","volume-title":"Craniofacial Growth in Man","author":"Dullemeyer P","year":"1971"},{"key":"e_1_2_1_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9416(65)90242-3"},{"key":"e_1_2_1_15_1","first-page":"185","article-title":"One case of microcephalia, heredosy\u2013philis and heredoalcoholism","volume":"32","author":"Filho M","year":"1924","journal-title":"Pediatria."},{"key":"e_1_2_1_16_1","first-page":"29","article-title":"Description of a great sepulchral mound","author":"Frazer W","year":"1879","journal-title":"Proc. Roy. Irish Acad."},{"key":"e_1_2_1_17_1","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1978.00500360036007"},{"key":"e_1_2_1_18_1","first-page":"7","volume-title":"Hemisphere Function in the Human Brain","author":"Geschwind N","year":"1974"},{"key":"e_1_2_1_19_1","unstructured":"Giacomini C (1890)I Cervelli dei Microcefali. Giornale Acad. Med. Turin. p.95."},{"key":"e_1_2_1_20_1","first-page":"102","article-title":"Radiogenic microcephaly","volume":"27","author":"Goldstein L","year":"1929","journal-title":"Arch. Neurol. Psychiat."},{"key":"e_1_2_1_21_1","first-page":"322","article-title":"Etiology of the ill\u2013health in children born after maternal pelvic irradiation. Pt II. Defective children born after post\u2013conception pelvic irradiation","volume":"22","author":"Goldstein L","year":"1929","journal-title":"Am J. Roentgenol."},{"key":"e_1_2_1_22_1","volume-title":"Atlas of the Human Face In Genetic Disorders","author":"Goodman RM","year":"1977"},{"key":"e_1_2_1_23_1","doi-asserted-by":"publisher","DOI":"10.1001\/archneurpsyc.1935.02250180155008"},{"key":"e_1_2_1_24_1","first-page":"35","article-title":"Congenital cataract following German measles in the mother","volume":"3","author":"Gregg NM","year":"1941","journal-title":"J. Opht. Soc. Australia"},{"key":"e_1_2_1_25_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00344938"},{"key":"e_1_2_1_26_1","first-page":"363","article-title":"The anatomy of a hydromicrocephalous brain","volume":"19","author":"Hill A","year":"1885","journal-title":"J. Anat. Phys."},{"key":"e_1_2_1_27_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4684-2484-3_8"},{"key":"e_1_2_1_28_1","first-page":"125","volume-title":"Transactions of the 3rd International Orthodontic Congress","author":"Hopkin GB","year":"1975"},{"key":"e_1_2_1_29_1","volume-title":"Cranial Variation in Man","author":"Howells WW","year":"1973"},{"key":"e_1_2_1_30_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajpa.1330010116"},{"key":"e_1_2_1_31_1","first-page":"304","article-title":"Notes on the microcephalic or idiot skull, and on the macrocephalic or hydrocephalic skull","author":"Humphry G","year":"1895","journal-title":"J. Anat. Phys."},{"key":"e_1_2_1_32_1","volume-title":"Paleoneurol\u2013ogy","author":"Kochetkova VI","year":"1978"},{"key":"e_1_2_1_33_1","first-page":"51","article-title":"Genetic study of microcephaly based on Japanese material","volume":"7","author":"Komai T","year":"1955","journal-title":"J. Hum. Genet."},{"key":"e_1_2_1_34_1","unstructured":"Krogman WM (1941)Growth of man. Tabulae Biologi\u2013cae Vol. 20."},{"key":"e_1_2_1_35_1","volume-title":"Syllabus in Roentgenographic Cephalometry","author":"Krogman WM","year":"1957"},{"key":"e_1_2_1_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(50)80131-2"},{"key":"e_1_2_1_37_1","volume-title":"The Fossil Evidence for Human Evolution","author":"LeGros Clark WE","year":"1964"},{"key":"e_1_2_1_38_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.1976.tb25499.x"},{"key":"e_1_2_1_39_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4684-4148-2_17"},{"key":"e_1_2_1_40_1","unstructured":"Martin CP (1935)Prehistoric Man in Ireland. London pp.184."},{"key":"e_1_2_1_41_1","volume-title":"Lehrbuch der Anthropologie","author":"Martin R","year":"1928"},{"key":"e_1_2_1_42_1","volume-title":"Foetal and Neonatal Pathology","author":"Morison JE","year":"1970"},{"key":"e_1_2_1_43_1","unstructured":"Morse D (1978)Ancient Disease in the Midwest. Ill. State. Mus. Rep. Invest. No. 15."},{"key":"e_1_2_1_44_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajpa.1330180406"},{"key":"e_1_2_1_45_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajpa.1330340315"},{"key":"e_1_2_1_46_1","doi-asserted-by":"publisher","DOI":"10.1080\/19485565.1975.9988168"},{"key":"e_1_2_1_47_1","series-title":"Smithsonian Cont. Anthro. No. 28","volume-title":"Identification of pathological conditions in human skeletal remains","author":"Ortner DJ","year":"1981"},{"key":"e_1_2_1_48_1","unstructured":"Richards GD andFenega G (1985)The archaeology of a Late Period (1100\u20131700 A. D.) village site from Central California. (In preparation.)"},{"key":"e_1_2_1_49_1","first-page":"1","article-title":"A case of microcephaly in an Aeneo\u2013lithic Yayoi period population in Japan","volume":"1","author":"Suzuki H","year":"1975","journal-title":"Bull. Natn. Sci. Mus. Series D"},{"key":"e_1_2_1_50_1","first-page":"642","article-title":"Microcephaly as a complication of pneumococcie meningitis","volume":"77","author":"Thelander HE","year":"1949","journal-title":"Amer. J. Dis. Child."},{"key":"e_1_2_1_51_1","doi-asserted-by":"publisher","DOI":"10.5962\/bhl.title.15880"},{"key":"e_1_2_1_52_1","doi-asserted-by":"crossref","DOI":"10.1136\/pgmj.13.141.259","volume-title":"A Text\u2013Book of Mental Deficiency (Amentia)","author":"Tredgold AF","year":"1937"},{"key":"e_1_2_1_53_1","volume-title":"Human Skeletal Remains","author":"Ubelaker DH","year":"1978"},{"key":"e_1_2_1_54_1","doi-asserted-by":"publisher","DOI":"10.1163\/187530146X00023"},{"key":"e_1_2_1_55_1","unstructured":"Virchow R (1857)Untersuchungen \u00fcber die entwick\u2013lung des sch\u00e4delgrundes. Gesunden und Krankhaften Zustande und \u00fcber den Einfluss derselben auf Scha\u00e4d\u2013elform Gesichtsbildung und Gehirnbau. Berlin: Georg Reimer Verlag."},{"key":"e_1_2_1_56_1","first-page":"1","article-title":"M\u00e9moire sur les microc\u00e9phales ou hommes singes","author":"Vogt C","year":"1866","journal-title":"M\u00e9m. Inst. Natl. Genevois."},{"key":"e_1_2_1_57_1","doi-asserted-by":"publisher","DOI":"10.2307\/1005610"},{"key":"e_1_2_1_58_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajpa.1330290305"},{"key":"e_1_2_1_59_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/96.3.641"},{"key":"e_1_2_1_60_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.816005"},{"key":"e_1_2_1_61_1","first-page":"111","article-title":"Microcephaly, mild mental retardation, short stature, and skeletal anomalies in siblings","volume":"124","author":"Zackai EH","year":"1972","journal-title":"Amer. J. Dis. Child"}],"container-title":["American Journal of Physical Anthropology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fajpa.1330680305","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ajpa.1330680305","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,20]],"date-time":"2023-10-20T20:26:38Z","timestamp":1697833598000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ajpa.1330680305"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1985,11]]},"references-count":60,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1985,11]]}},"alternative-id":["10.1002\/ajpa.1330680305"],"URL":"https:\/\/doi.org\/10.1002\/ajpa.1330680305","archive":["Portico"],"relation":{},"ISSN":["0002-9483","1096-8644"],"issn-type":[{"value":"0002-9483","type":"print"},{"value":"1096-8644","type":"electronic"}],"subject":[],"published":{"date-parts":[[1985,11]]}}}