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Anthropometric measurements, including head length and breadth, minimum frontal diameter, and head circumference, were obtained on 38 PLWS individuals (21 with chromosome 15 deletions) with an age range from 2 weeks to 39 years. No anthropometric differences were found between the two chromosome subgroups. A relative deceleration in the growth of certain craniofacial dimensions (head circumference and length) is suggested by the negative correlations between age and Z\u2010scores for the measurements. Raw values for minimum frontal diameter and head breadth were near or below the 5th percentile curve, while almost all values for head length and circumference fell within normal limits. The data support suggestions that dolichocephaly be considered an early diagnostic feature of PLWS. Furthermore, the status of narrow bifrontal diameter as a major feature of PLWS is confirmed.<\/jats:p>","DOI":"10.1002\/ajpa.1330740405","type":"journal-article","created":{"date-parts":[[2006,2,4]],"date-time":"2006-02-04T09:55:24Z","timestamp":1139046924000},"page":"459-464","source":"Crossref","is-referenced-by-count":20,"title":["Craniofacial variation and growth in the Prader\u2010Labhart\u2010Willi syndrome"],"prefix":"10.1002","volume":"74","author":[{"given":"F. John","family":"Meaney","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Merlin G.","family":"Butler","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,4,27]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-0004.1985.tb01213.x"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.1320260224"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.1320230307"},{"key":"e_1_2_1_5_1","volume-title":"The Measurement of Human Growth","author":"Cameron N","year":"1984"},{"key":"e_1_2_1_6_1","first-page":"69","volume-title":"The Prader\u2010Willi Syndrome","author":"Dunn HG","year":"1981"},{"key":"e_1_2_1_7_1","volume-title":"Anthropometry of the Head and Face in Medicine","author":"Farkas CG","year":"1981"},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(72)80297-X"},{"key":"e_1_2_1_9_1","first-page":"196","volume-title":"Human Biology: An Introduction to Human Evolution, Variation, Growth and Ecology","author":"Harrison GA","year":"1977"},{"key":"e_1_2_1_10_1","first-page":"27","volume-title":"The Prader\u2010Willi Syndrome","author":"Holm VA","year":"1981"},{"key":"e_1_2_1_11_1","unstructured":"Meaney FJandButler MG(1987) The developing role of anthropologists in medical genetics: anthropometric assessment of the Prader\u2010Labhart\u2010Willi syndrome as an illustration.Med Anthropol.(in press)."},{"key":"e_1_2_1_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.1320250221"},{"key":"e_1_2_1_13_1","first-page":"33","volume-title":"Endocrine Genetics and Genetics of Growth","author":"Opitz JM","year":"1985"},{"key":"e_1_2_1_14_1","first-page":"1260","article-title":"Ein syndrom von adipositas, kleinwuchs, Kryptorchismus und Oligophrenie nach myatonieartigen Zustand im Neugeborenenalter","volume":"86","author":"Prader A","year":"1956","journal-title":"Schweiz Med Wochenschr"},{"key":"e_1_2_1_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-0004.1984.tb02001.x"},{"key":"e_1_2_1_16_1","volume-title":"Recognizable Patterns of Human Malformation: Genetic, Embryologic and Clinical Aspects","author":"Smith DW","year":"1976"},{"key":"e_1_2_1_17_1","volume-title":"Anthropometry of Infants, Children and Youths to Age 18 for Product Safety Design SP\u2010450","author":"Snyder RG","year":"1977"},{"key":"e_1_2_1_18_1","series-title":"International Biological Programme Handbook No. 9","volume-title":"Human Biology: A Guide to Field Methods","author":"Weiner JS","year":"1969"},{"key":"e_1_2_1_19_1","first-page":"883","volume-title":"Birth Defects Compendium","author":"Zellweger H","year":"1979"},{"key":"e_1_2_1_20_1","first-page":"55","volume-title":"The Prader\u2010Willi Syndrome","author":"Zellweger H","year":"1981"},{"key":"e_1_2_1_21_1","first-page":"588","article-title":"Syndrome of hypotonia\u2010hypomentia\u2010hypogonadism\u2010obesity (HHHO) or Prader\u2010Willi syndrome","volume":"115","author":"Zellweger H","year":"1968","journal-title":"Am. 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