{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T11:22:18Z","timestamp":1761823338447},"reference-count":65,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2011,3,1]],"date-time":"2011-03-01T00:00:00Z","timestamp":1298937600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["American J Phys Anthropol"],"published-print":{"date-parts":[[2011,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The prevalence of adult\u2010type hypolactasia varies ethnically and geographically among populations. A C\/T\u201313910 single nucleotide polymorphism (SNP) upstream of the lactase gene is known to be associated with lactase non\u2010persistence in Europeans. The aim of this study was to determine the prevalence of lactase persistent and non\u2010persistent genotypes in current Hungarian\u2010speaking populations and in ancient bone samples of classical conquerors and commoners from the 10th\u201311th centuries from the Carpathian basin; 181 present\u2010day Hungarian, 65 present\u2010day Sekler, and 23 ancient samples were successfully genotyped for the C\/T\u201013910 SNP by the dCAPS PCR\u2010RFLP method. Additional mitochondrial DNA testing was also carried out. In ancient Hungarians, the T\u201013910 allele was present only in 11% of the population, and exclusively in commoners of European mitochondrial haplogroups who may have been of pre\u2010Hungarian indigenous ancestry. This is despite animal domestication and dairy products having been introduced into the Carpathian basin early in the Neolithic Age. This anomaly may be explained by the Hungarian use of fermented milk products, their greater consumption of ruminant meat than milk, cultural differences, or by their having other lactase\u2010regulating genetic polymorphisms than C\/T\u201013910. The low prevalence of lactase persistence provides additional information on the Asian origin of Hungarians. Present\u2010day Hungarians have been assimilated with the surrounding European populations, since they do not differ significantly from the neighboring populations in their possession of mtDNA and C\/T\u201013910 variants. Am J Phys Anthropol, 2011. \u00a9 2011 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/ajpa.21490","type":"journal-article","created":{"date-parts":[[2011,3,3]],"date-time":"2011-03-03T00:46:17Z","timestamp":1299113177000},"page":"262-269","source":"Crossref","is-referenced-by-count":23,"title":["Comparison of lactase persistence polymorphism in ancient and present\u2010day Hungarian populations"],"prefix":"10.1002","volume":"145","author":[{"given":"D\u00f3ra","family":"Nagy","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gy\u00f6ngyv\u00e9r","family":"T\u00f6m\u00f6ry","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bernadett","family":"Cs\u00e1nyi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Erika","family":"Bog\u00e1csi\u2010Szab\u00f3","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"\u00c1gnes","family":"Czibula","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katalin","family":"Priskin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Olga","family":"Bede","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L\u00e1szl\u00f3","family":"Bartosiewicz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C. 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