{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T15:29:23Z","timestamp":1790004563708,"version":"4.0.1"},"reference-count":91,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2012,12,24]],"date-time":"2012-12-24T00:00:00Z","timestamp":1356307200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["American J Phys Anthropol"],"published-print":{"date-parts":[[2013,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Treponematosis has been one of the most studied and debated infectious diseases in paleopathology, particularly from the standpoint of its origin, evolution, and transmission. This study links evidence for treponematosis in skeletons from the 14th\u201316th century AD cemetery of the Augustinian friary of Hull Magistrates Court, England, with data from stable isotope analysis to test the hypothesis that the people with treponemal disease buried at this site were not locally born and raised. The objective is to explore the potential of using stable isotope data to track the place of origin and extent of mobility of individuals with an infectious disease. Dental enamel samples of 12 skeletons were selected for strontium (<jats:sup>87<\/jats:sup>Sr\/<jats:sup>86<\/jats:sup>Sr ratio) and oxygen (\u03b4<jats:sup>18<\/jats:sup>O) stable isotope analysis based on the presence (six \u2010 diseased) or absence (six \u2010 controls) of bone changes associated with treponemal disease. The oxygen isotope ratios of all but three individuals (1047, 1121, 823) overlapped at two standard deviations with the inferred local precipitation range, and only one individual (1216) had a strontium isotope ratio outside the regional range. Two of the four had probable\/possible treponemal bone changes. Those with treponemal bone changes were not demonstrably more likely to be migrants than those without such lesions. However, because of extensive documentary evidence for trade with the Baltic Sea area, and for merchants from towns such as Stralsund, Danzig and Elbing being in Hull, it is very plausible that the four migrants came from the Baltic area or even southern Sweden. Am J Phys Anthropol, 2013. \u00a9 2012 Wiley Periodicals, Inc.<\/jats:p>","DOI":"10.1002\/ajpa.22203","type":"journal-article","created":{"date-parts":[[2012,12,24]],"date-time":"2012-12-24T08:13:33Z","timestamp":1356336813000},"page":"273-285","source":"Crossref","is-referenced-by-count":24,"title":["Isotopic tracing of the impact of mobility on infectious disease: The origin of people with treponematosis buried in hull, England, in the late medieval period"],"prefix":"10.1002","volume":"150","author":[{"given":"C.A.","family":"Roberts","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.R.","family":"Millard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.M.","family":"Nowell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.R.","family":"Gr\u00f6cke","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.G.","family":"Macpherson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.G.","family":"Pearson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.H.","family":"Evans","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2012,12,24]]},"reference":[{"key":"e_1_2_10_2_1","first-page":"371","volume-title":"A History of the County of York East Riding: Volume 1: The City of Kingston upon Hull","author":"Allison KJ.","year":"1969"},{"key":"e_1_2_10_3_1","unstructured":"ArmelagosGJ.1998.The viral superhighway. The Sciences January\/February:24\u201329."},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1086\/203691"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1098\/rspb.2004.2885"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jas.2011.02.017"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/oa.662"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0883-2927(99)00075-X"},{"key":"e_1_2_10_9_1","first-page":"2091","article-title":"The limits of biomolecular palaeopathology: ancient DNA cannot be used to study venereal syphilis","volume":"34","author":"Bouwman AS","year":"2005","journal-title":"J Archaeol Sci"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1029\/2003WR002086"},{"key":"e_1_2_10_11_1","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1016\/j.scitotenv.2006.10.019","article-title":"Human lead exposure in a late 19th century mental asylum population","volume":"372","author":"Bower NW","year":"2007","journal-title":"Sci Total Environ"},{"key":"e_1_2_10_12_1","volume-title":"Hull Magistrates Court skeletal report","author":"Boylston A","year":"2001"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1039\/c2ja10335d"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0033822200033865"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1475-4754.2000.tb00893.x"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.2307\/2844418"},{"key":"e_1_2_10_17_1","first-page":"480","volume-title":"The myth of syphilis. The natural history of treponematosis in North America","author":"Brothwell D.","year":"2005"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0003598X0009298X"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0883-2927(99)00069-4"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-3156.1998.00337.x"},{"key":"e_1_2_10_21_1","first-page":"519","volume-title":"Whithorn and St Ninian","author":"Cardy A.","year":"1997"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chemgeo.2006.02.015"},{"key":"e_1_2_10_23_1","unstructured":"WR Childs 1986 Yorkshire Archaeological Society Leeds"},{"key":"e_1_2_10_24_1","volume-title":"The trade and shipping of Hull, 1300\u20101500. East Yorkshire Local History Society Series 43","author":"Childs WR.","year":"1990"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajpa.21371"},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.quascirev.2003.06.016"},{"key":"e_1_2_10_27_1","doi-asserted-by":"publisher","DOI":"10.5194\/hess-7-183-2003"},{"key":"e_1_2_10_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhevol.2008.06.006"},{"key":"e_1_2_10_29_1","volume-title":"The archaeology of York 12\/1","author":"Dawes JD","year":"1980"},{"key":"e_1_2_10_30_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0000575"},{"key":"e_1_2_10_31_1","doi-asserted-by":"publisher","DOI":"10.1130\/0091-7613(2001)029<0031:SSIEFA>2.0.CO;2"},{"key":"e_1_2_10_32_1","unstructured":"O Dutour G Palfi J Berato J\u2010P Brun 1994 Editions Errance\/Centre Archaeologique du Var Toulon"},{"key":"e_1_2_10_33_1","volume-title":"The post\u2010excavation assessment and updated project design for the Hull Magistrates Courts site. Limited distribution client report for English Heritage and the Lord Chancellor's Department","author":"Evans DH.","year":"1998"},{"key":"e_1_2_10_34_1","first-page":"59","volume-title":"L\u00fcbecker Kolloquium zur Stadtarch\u00e4ologie im Hanseraum II","author":"Evans DH.","year":"1999"},{"key":"e_1_2_10_35_1","unstructured":"EvansDH.2000. Buried with the Friars. Br Archaeol53:18\u201323."},{"key":"e_1_2_10_36_1","first-page":"63","volume-title":"L\u00fcbecker Kolloquium zur Stadtarch\u00e4ologie im Hanseraum VI: Luxus und Lifestyle","author":"Evans DH.","year":"2008"},{"key":"e_1_2_10_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jas.2005.07.011"},{"key":"e_1_2_10_38_1","doi-asserted-by":"publisher","DOI":"10.1144\/0016-76492009-090"},{"key":"e_1_2_10_39_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(08)70065-3"},{"key":"e_1_2_10_40_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2334-10-330"},{"key":"e_1_2_10_41_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.apgeochem.2010.12.006"},{"key":"e_1_2_10_42_1","volume-title":"Requiem. The Medieval monastic cemetery in Britain","author":"Gilchrist R","year":"2005"},{"key":"e_1_2_10_43_1","first-page":"43","volume-title":"The Black Death cemetery","author":"Grainger I","year":"2008"},{"key":"e_1_2_10_44_1","doi-asserted-by":"publisher","DOI":"10.1023\/B:BIOG.0000025743.34079.d3"},{"key":"e_1_2_10_45_1","unstructured":"CJ. Hackett 1976 Springer\u2010Verlag Berlin"},{"key":"e_1_2_10_46_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0000148"},{"key":"e_1_2_10_47_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajpa.21613"},{"key":"e_1_2_10_48_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1475-4754.1989.tb01007.x"},{"key":"e_1_2_10_49_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0033822200063463"},{"key":"e_1_2_10_50_1","unstructured":"JayM MontgomeryJ.2008. Copper Age. Br Archaeol July August:26."},{"key":"e_1_2_10_51_1","doi-asserted-by":"publisher","DOI":"10.1345\/aph.1K086"},{"key":"e_1_2_10_52_1","volume-title":"Medieval merchants","author":"Kermode J.","year":"1998"},{"key":"e_1_2_10_53_1","volume-title":"In the wake of contact: biological responses to contact","author":"Larsen CS","year":"1994"},{"key":"e_1_2_10_54_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.socscimed.2004.03.015"},{"key":"e_1_2_10_55_1","doi-asserted-by":"publisher","DOI":"10.1002\/qj.49710042511"},{"key":"e_1_2_10_56_1","doi-asserted-by":"publisher","DOI":"10.1002\/oa.1210"},{"key":"e_1_2_10_57_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajpa.10132"},{"key":"e_1_2_10_58_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajpa.1330350603"},{"key":"e_1_2_10_59_1","volume-title":"Are modern environments bad for human health? Revisiting the Second Epidemiological Transition","author":"Millard AR","year":"2012"},{"key":"e_1_2_10_60_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajpa.21100"},{"key":"e_1_2_10_61_1","doi-asserted-by":"publisher","DOI":"10.3201\/eid1511.090718"},{"key":"e_1_2_10_62_1","volume-title":"Lead and strontium isotope compositions of human dental tissues as an indicator of ancient exposure and population dynamics","author":"Montgomery J.","year":"2002"},{"key":"e_1_2_10_63_1","first-page":"122","volume-title":"The social archaeology of human remains","author":"Montgomery J","year":"2006"},{"key":"e_1_2_10_64_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajpa.20111"},{"key":"e_1_2_10_65_1","doi-asserted-by":"publisher","DOI":"10.1177\/00220345630420062701"},{"key":"e_1_2_10_66_1","first-page":"e184","author":"Mulligan CJ","year":"2008","journal-title":"in Treponema pallidum"},{"key":"e_1_2_10_67_1","volume-title":"Identification of pathological conditions in human skeletal remains","author":"Ortner DJ.","year":"2003"},{"key":"e_1_2_10_68_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0003598X00068034"},{"key":"e_1_2_10_69_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajpa.21524"},{"key":"e_1_2_10_70_1","volume-title":"The myth of syphilis. The natural history of treponematosis in North America","author":"Powell ML","year":"2005"},{"key":"e_1_2_10_71_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijms.2004.11.028"},{"key":"e_1_2_10_72_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0033822200034202"},{"key":"e_1_2_10_73_1","first-page":"2448","volume-title":"Diagnosis of bone and joint disorders","author":"Resnick D","year":"1995"},{"key":"e_1_2_10_74_1","doi-asserted-by":"publisher","DOI":"10.1006\/jasc.1998.0387"},{"key":"e_1_2_10_75_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0012-821X(01)00427-7"},{"key":"e_1_2_10_76_1","doi-asserted-by":"publisher","DOI":"10.1093\/acprof:osobl\/9780195389807.003.0072"},{"key":"e_1_2_10_77_1","first-page":"101","volume-title":"L'origine de la syphilis en Europe, avant ou apr\u00e8s 1493?","author":"Roberts CA.","year":"1994"},{"key":"e_1_2_10_78_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jas.2010.11.015"},{"key":"e_1_2_10_79_1","doi-asserted-by":"publisher","DOI":"10.1016\/0305-4403(91)90065-W"},{"key":"e_1_2_10_80_1","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1017\/S0033822200042491","article-title":"Validating and improving archaeological phasing at St Mary Spital, London","volume":"49","author":"Siddell J","year":"2007","journal-title":"Radiocarbon"},{"key":"e_1_2_10_81_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1610-0387.2008.06490.x"},{"key":"e_1_2_10_82_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.olq.0000149848.03733.c1"},{"key":"e_1_2_10_83_1","first-page":"85","article-title":"Megaliths and mobility in south\u2010western Sweden","volume":"28","author":"Sjogren KG","year":"2009","journal-title":"Investigating relationships between a local society and its neighbours using strontium isotopes. J Anthropol Archaeol"},{"key":"e_1_2_10_84_1","first-page":"109","volume-title":"L'origine de la syphilis en Europe, avant ou apr\u00e8s 1493?","author":"Stirland A.","year":"1994"},{"key":"e_1_2_10_85_1","volume-title":"Disease in transition. Anthropological and epidemiological approaches","author":"Swedlund AC","year":"1990"},{"key":"e_1_2_10_86_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0883-2927(02)00181-6"},{"key":"e_1_2_10_87_1","first-page":"39","volume-title":"Biogeochemical approaches to paleodietary analysis","author":"van Klinken G\u2010J","year":"2000"},{"key":"e_1_2_10_88_1","doi-asserted-by":"publisher","DOI":"10.1021\/es000169c"},{"key":"e_1_2_10_89_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodchem.2009.04.125"},{"key":"e_1_2_10_90_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajpa.20335"},{"key":"e_1_2_10_91_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jas.2007.02.007"},{"key":"e_1_2_10_92_1","doi-asserted-by":"publisher","DOI":"10.1086\/204084"}],"container-title":["American Journal of Physical Anthropology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fajpa.22203","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ajpa.22203","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,11]],"date-time":"2023-10-11T01:23:24Z","timestamp":1696987404000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ajpa.22203"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,12,24]]},"references-count":91,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2013,2]]}},"alternative-id":["10.1002\/ajpa.22203"],"URL":"https:\/\/doi.org\/10.1002\/ajpa.22203","archive":["Portico"],"relation":{},"ISSN":["0002-9483","1096-8644"],"issn-type":[{"value":"0002-9483","type":"print"},{"value":"1096-8644","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,12,24]]}}}