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LP in the Angolan Namib is represented by the \u221214010*C allele, which is associated with a predominant haplotype that is shared with other southern and eastern African populations. While LP was found to be more frequent in foragers than in pastoralists, the frequencies of the two APOL1 variants associated with HAT\u2010resistance (G1 and G2) did not differ between the two groups. The G1 allele is mostly associated with a single widespread haplotype. The G2 allele is linked to several haplotypes that are molecularly related to haplotypes found in other African Bantu\u2010speaking populations. The putatively archaic G3 variant displayed more intra\u2010allelic diversity in Africa than in Europe.<\/jats:p><\/jats:sec><jats:sec><jats:label\/><jats:p><jats:bold>Discussion<\/jats:bold>: The LP adaptation was carried to southern Africa by non\u2010Bantu speaking pastoralists from eastern Africa, but an obvious link between its presence in southern Angola and groups speaking languages of the Khoe\u2010Kwadi family, as previously found in other areas, could not be confirmed. The presence of APOL1 variants G1 and G2 is linked to the Bantu expansions. Our results suggest that the G3 variant was retained in modern humans by incomplete lineage sorting.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ajpa.23042","type":"journal-article","created":{"date-parts":[[2016,7,12]],"date-time":"2016-07-12T07:19:56Z","timestamp":1468307996000},"page":"436-447","source":"Crossref","is-referenced-by-count":18,"title":["Food and pathogen adaptations in the Angolan Namib desert: Tracing the spread of lactase persistence and human African trypanosomiasis resistance into southwestern Africa"],"prefix":"10.1002","volume":"161","author":[{"given":"Joana C.","family":"Pinto","sequence":"first","affiliation":[{"name":"CIBIO\/InBIO: Research Centre in Biodiversity and Genetic Resources Vair\u00e3o 4485\u2010661 Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandra","family":"Oliveira","sequence":"additional","affiliation":[{"name":"CIBIO\/InBIO: Research Centre in Biodiversity and Genetic Resources Vair\u00e3o 4485\u2010661 Portugal"},{"name":"Departamento de Biologia Faculdade de Ci\u00eancias, Universidade do Porto Porto 4169\u2010007 Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S\u00e9rgio","family":"Teixeira","sequence":"additional","affiliation":[{"name":"CIBIO\/InBIO: Research Centre in Biodiversity and Genetic Resources Vair\u00e3o 4485\u2010661 Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dayana","family":"Martins","sequence":"additional","affiliation":[{"name":"ISCED\/Hu\u00edla\u2014Instituto Superior de Ci\u00eancias da Educa\u00e7\u00e3o Lubango Angola"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne\u2010Maria","family":"Fehn","sequence":"additional","affiliation":[{"name":"CIBIO\/InBIO: Research Centre in Biodiversity and Genetic Resources Vair\u00e3o 4485\u2010661 Portugal"},{"name":"Max Planck Institute for the Science of Human History Jena 07745 Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Teresa","family":"A\u00e7o","sequence":"additional","affiliation":[{"name":"Centro de Estudos do Deserto (CEDO) Namibe Angola"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Magdalena","family":"Gay\u00e0\u2010Vidal","sequence":"additional","affiliation":[{"name":"CIBIO\/InBIO: Research Centre in Biodiversity and Genetic Resources Vair\u00e3o 4485\u2010661 Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jorge","family":"Rocha","sequence":"additional","affiliation":[{"name":"CIBIO\/InBIO: Research Centre in Biodiversity and Genetic Resources Vair\u00e3o 4485\u2010661 Portugal"},{"name":"Departamento de Biologia Faculdade de Ci\u00eancias, Universidade do Porto Porto 4169\u2010007 Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,7,12]]},"reference":[{"key":"e_1_2_6_2_1","volume-title":"Bushmen and Other Non\u2010Bantu Peoples of Angola: Three Lectures","author":"Almeida A.","year":"1965"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11250-011-9868-3"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.3378\/027.083.0102"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.molbev.a026036"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1017\/CBO9781139166508"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1093\/molbev\/mss207"},{"key":"e_1_2_6_8_1","first-page":"31","article-title":"Was there an interchange between cushitic pastoralists and khoesan speakers in the prehistory of southern africa and how can this be detected?","volume":"20","author":"Blench R.","year":"2009","journal-title":"SUGIA"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cub.2014.02.041"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(09)60829-1"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00439-005-1322-z"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2148-9-80"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.2307\/1157174"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0021853700008835"},{"key":"e_1_2_6_15_1","volume-title":"Etnografia do sudoeste de Angola. 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