{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,19]],"date-time":"2026-04-19T18:00:20Z","timestamp":1776621620848,"version":"3.51.2"},"reference-count":75,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2018,10,24]],"date-time":"2018-10-24T00:00:00Z","timestamp":1540339200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100007369","name":"Institut de France","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007369","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007543","name":"Grantov\u00e1 Agentura, Univerzita Karlova","doi-asserted-by":"publisher","award":["250 057"],"award-info":[{"award-number":["250 057"]}],"id":[{"id":"10.13039\/100007543","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["American J Phys Anthropol"],"published-print":{"date-parts":[[2018,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>Recent investigations have evaluated the influence of body composition on long bones in order to overcome the limits of body mass (BM) estimation methods and eventually lead to studying nutrition in past populations. Knowing how fat mass (FM) and fat\u2010free mass (FFM) impact the skeleton would also enhance the understanding of mobility, activity, and locomotion derived from bone architecture. We investigated the relationship between BM and composition, and the architecture of the entire tibial and femoral diaphyses in an adult sample representative of a wide range of variation in age, BM, and composition.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and methods<\/jats:title><jats:p>Body composition was measured directly from 78 whole\u2010body CT scans for which the age, sex, BM, and stature were recorded. The entire diaphyseal thickness, volume, curvature, and cross\u2010sectional geometry parameters of both the femur and tibia were numerically extracted.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>FM correlates with large portions of the femoral thickness in females only. FFM correlates with the femoral diaphysis in males but not in females. FFM correlates with the tibia architecture in both sexes, while FM is correlated in males exclusively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Discussion<\/jats:title><jats:p>BM and body components influence the architecture of the diaphysis of lower limb long bones in sex\u2010specific patterns that are mostly reflected in their thickness and can be recorded, in some cases, for their strength, rigidity, and volume. Our results suggest that (1) long bone diaphyses should be thoroughly studied, as a whole, when possible; and (2) BM and body components should be accounted for when deriving activity, mobility, or locomotion patterns from cortical bone.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ajpa.23713","type":"journal-article","created":{"date-parts":[[2018,10,24]],"date-time":"2018-10-24T23:01:50Z","timestamp":1540422110000},"page":"813-826","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Architecture of the femoral and tibial diaphyses in relation to body mass and composition: Research from whole\u2010body CT scans of adult humans"],"prefix":"10.1002","volume":"167","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2909-9505","authenticated-orcid":false,"given":"Aliz\u00e9","family":"Lacoste Jeanson","sequence":"first","affiliation":[{"name":"Laboratory of 3D Imaging and Analytical Methods, Faculty of Natural Sciences, Department of Anthropology and Human Genetics Charles University  Praha 2 Czech Republic"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1445-3871","authenticated-orcid":false,"given":"Fr\u00e9d\u00e9ric","family":"Santos","sequence":"additional","affiliation":[{"name":"PACEA, UMR 5199, CNRS Universit\u00e9 de Bordeaux, B\u00e2timent B8  Talence All\u00e9e Geoffroy Saint Hilaire, CS 50023, Talence France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chiara","family":"Villa","sequence":"additional","affiliation":[{"name":"Section of Forensic Pathology, Department of Forensic Medicine, Faculty of Health and Medical Sciences University of Copenhagen  Copenhagen \u00d8 Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jytte","family":"Banner","sequence":"additional","affiliation":[{"name":"Section of Forensic Pathology, Department of Forensic Medicine, Faculty of Health and Medical Sciences University of Copenhagen  Copenhagen \u00d8 Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jaroslav","family":"Br\u016f\u017eek","sequence":"additional","affiliation":[{"name":"Laboratory of 3D Imaging and Analytical Methods, Faculty of Natural Sciences, Department of Anthropology and Human Genetics Charles University  Praha 2 Czech Republic"},{"name":"PACEA, UMR 5199, CNRS Universit\u00e9 de Bordeaux, B\u00e2timent B8  Talence All\u00e9e Geoffroy Saint Hilaire, CS 50023, Talence France"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2018,10,24]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1556-4029.2010.01648.x"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1249\/MSS.0b013e3181a8c4b6"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1359\/jbmr.2001.16.6.1108"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1359\/jbmr.090307"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajpa.21271"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajhb.1310010616"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajpa.23396"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajhb.22606"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajpa.23315"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12520-015-0251-6"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12520-015-0252-5"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jocd.2012.02.013"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/1556-4029.12579"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1097\/ID.0000000000000021"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/PL00004150"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.nutr.17.1.527"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajpa.10256"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1002\/jbmr.468"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00198-013-2592-2"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.14310\/horm.2002.1315"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0378-5122(01)00205-5"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI111040"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4613-1473-8_28"},{"key":"e_1_2_6_25_1","doi-asserted-by":"publisher","DOI":"10.7717\/peerj.3302"},{"key":"e_1_2_6_26_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajhb.23123"},{"key":"e_1_2_6_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.forsciint.2017.10.026"},{"key":"e_1_2_6_28_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajpa.1123"},{"key":"e_1_2_6_29_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajpa.22710"},{"key":"e_1_2_6_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhevol.2005.08.002"},{"key":"e_1_2_6_31_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajpa.22626"},{"key":"e_1_2_6_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.forsciint.2017.03.003"},{"key":"e_1_2_6_33_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1556-4029.2011.01819.x"},{"key":"e_1_2_6_34_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajpa.22889"},{"key":"e_1_2_6_35_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajhb.22965"},{"key":"e_1_2_6_36_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajpa.20155"},{"key":"e_1_2_6_37_1","volume-title":"Adaptation structurelle des os du membre sup\u00e9rieur et de la clavicule \u00e0 l'activit\u00e9: Analyse de l'asym\u00e9trie des propri\u00e9t\u00e9s g\u00e9om\u00e9triques de sections transverses et de mesures lin\u00e9aires dans une population identifi\u00e9e (collection SIMON)","author":"Perr\u00e9ard Lopreno G.","year":"2007"},{"key":"e_1_2_6_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bone.2004.05.008"},{"key":"e_1_2_6_39_1","first-page":"1","article-title":"Relationship between body mass, lean mass, fat mass, and limb bone cross\u2010sectional geometry: Implications for estimating body mass and physique from the skeleton","volume":"00","author":"Pomeroy E.","year":"2018","journal-title":"American Journal of Physical Anthropology"},{"key":"e_1_2_6_40_1","volume-title":"Caract\u00e9risation de l'endostructure et des propri\u00e9t\u00e9s biom\u00e9caniques de la diaphyse f\u00e9morale: la signature de la bip\u00e9die et la reconstruction des pal\u00e9o\u2010r\u00e9pertoires posturaux et locomoteurs des hominines","author":"Puymerail L.","year":"2011"},{"key":"e_1_2_6_41_1","first-page":"S29","article-title":"Architecture de la diaphyse f\u00e9morale et \u00e9valuation quantitative de l'influence de la masse musculaire et de la conformation pelvienne chez L'homo sapiens","volume":"24","author":"Puymerail L.","year":"2012","journal-title":"Bulletin et M\u00e9moires de la Societe d'Anthropologie de Paris"},{"key":"e_1_2_6_42_1","unstructured":"R Development Core team. (2015). R: A language and environment for statistical computing. Retrieved fromhttp:\/\/www.R-project.org. Accessed September 21 2018."},{"key":"e_1_2_6_43_1","doi-asserted-by":"publisher","DOI":"10.1016\/S8756-3282(02)00864-5"},{"key":"e_1_2_6_44_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00198-007-0492-z"},{"key":"e_1_2_6_45_1","doi-asserted-by":"publisher","DOI":"10.1016\/S8756-3282(00)00327-6"},{"key":"e_1_2_6_46_1","first-page":"893","article-title":"Adipose\u2010tissue determinations in cadavers\u2014A comparison between cross\u2010sectional Planimetry and computed\u2010tomography","volume":"14","author":"R\u00f6ssner S.","year":"1990","journal-title":"International Journal of Obesity"},{"key":"e_1_2_6_47_1","doi-asserted-by":"publisher","DOI":"10.1016\/0047-2484(87)90069-8"},{"key":"e_1_2_6_48_1","doi-asserted-by":"publisher","DOI":"10.1159\/000156413"},{"key":"e_1_2_6_49_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajpa.1330370605"},{"key":"e_1_2_6_50_1","first-page":"71","volume-title":"Biological anthropology of the human skeleton","author":"Ruff C. B.","year":"2000"},{"key":"e_1_2_6_51_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajpa.10117"},{"key":"e_1_2_6_52_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajpa.1330600308"},{"key":"e_1_2_6_53_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajpa.1330600309"},{"key":"e_1_2_6_54_1","doi-asserted-by":"publisher","DOI":"10.1002\/jor.1100060613"},{"key":"e_1_2_6_55_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1502932112"},{"key":"e_1_2_6_56_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajpa.20371"},{"key":"e_1_2_6_57_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhevol.2006.02.001"},{"key":"e_1_2_6_58_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhevol.2004.11.009"},{"key":"e_1_2_6_59_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajpa.1330860306"},{"key":"e_1_2_6_60_1","doi-asserted-by":"publisher","DOI":"10.1038\/nmeth.2019"},{"key":"e_1_2_6_61_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bone.2013.05.012"},{"key":"e_1_2_6_62_1","doi-asserted-by":"publisher","DOI":"10.1210\/jcem.86.10.7960"},{"key":"e_1_2_6_63_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00223-005-0037-4"},{"key":"e_1_2_6_64_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhevol.2010.06.002"},{"key":"e_1_2_6_65_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajpa.21064"},{"key":"e_1_2_6_66_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajpa.21363"},{"key":"e_1_2_6_67_1","doi-asserted-by":"publisher","DOI":"10.1259\/bjr\/38447238"},{"key":"e_1_2_6_68_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajpa.1330910405"},{"key":"e_1_2_6_69_1","doi-asserted-by":"publisher","DOI":"10.1359\/jbmr.071016"},{"key":"e_1_2_6_70_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajpa.1330930102"},{"key":"e_1_2_6_71_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1402439111"},{"key":"e_1_2_6_72_1","doi-asserted-by":"publisher","DOI":"10.1111\/cpf.12284"},{"key":"e_1_2_6_73_1","doi-asserted-by":"publisher","DOI":"10.1002\/hup.2387"},{"key":"e_1_2_6_74_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajpa.22674"},{"key":"e_1_2_6_75_1","volume-title":"Physical status: The use and interpretation of anthropometry","author":"WHO Expert Committee","year":"1995"},{"key":"e_1_2_6_76_1","doi-asserted-by":"publisher","DOI":"10.1007\/s001980170097"}],"container-title":["American Journal of Physical Anthropology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fajpa.23713","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ajpa.23713","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,15]],"date-time":"2023-09-15T15:11:13Z","timestamp":1694790673000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ajpa.23713"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,10,24]]},"references-count":75,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2018,12]]}},"alternative-id":["10.1002\/ajpa.23713"],"URL":"https:\/\/doi.org\/10.1002\/ajpa.23713","archive":["Portico"],"relation":{},"ISSN":["0002-9483","1096-8644"],"issn-type":[{"value":"0002-9483","type":"print"},{"value":"1096-8644","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,10,24]]},"assertion":[{"value":"2018-03-13","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-08-29","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-10-24","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}