{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T16:11:31Z","timestamp":1792253491165,"version":"4.4.0"},"reference-count":20,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2020,9,11]],"date-time":"2020-09-11T00:00:00Z","timestamp":1599782400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100009193","name":"Marsden Fund","doi-asserted-by":"publisher","award":["18\u2010UOO\u2010028"],"award-info":[{"award-number":["18\u2010UOO\u2010028"]}],"id":[{"id":"10.13039\/501100009193","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["American J Phys Anthropol"],"published-print":{"date-parts":[[2021,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The histological identification of interglobular dentine (IGD) in archeological human remains with macroscopic evidence of rickets has opened a promising new avenue for the investigation of metabolic disease in the past. Recent paleopathological studies have shown that histological analysis of archeological human teeth may allow the identification of periods of vitamin D deficiency occurring within very narrow developmental\u2009 windows, yielding new information on the seasonality or even maternal\u2010fetal transmission of this disease. However, currently available techniques for recording IGD rely on subjective scoring systems or visual estimations, potentially leaving them open to inter and intra\u2010observer error and rendering comparisons of datasets difficult. Here we describe a new imaging protocol that utilizes open access software and may yield more objective and quantitative data on the amount of IGD present within a dentinal region of interest. We demonstrate that grayscale histograms in FIJI\u00ae\/ImageJ\u00ae might be used to provide less subjective estimates of the percentage of a region of interest affected by IGD. Application of this technique may enable more accurate comparison of datasets between researchers.<\/jats:p>","DOI":"10.1002\/ajpa.24143","type":"journal-article","created":{"date-parts":[[2020,9,24]],"date-time":"2020-09-24T12:53:21Z","timestamp":1600952001000},"page":"144-148","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["An image analysis protocol for the quantification of interglobular dentine in anthropological tooth sections"],"prefix":"10.1002","volume":"174","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0516-785X","authenticated-orcid":false,"given":"Anne Marie E.","family":"Snoddy","sequence":"first","affiliation":[{"name":"Department of Anatomy University of Otago  Dunedin New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9769-2706","authenticated-orcid":false,"given":"Justyna J.","family":"Miszkiewicz","sequence":"additional","affiliation":[{"name":"School of Archaeology and Anthropology, Australian National University, College of Arts and Sciences  Canberra Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carolina","family":"Loch","sequence":"additional","affiliation":[{"name":"Sir John Walsh Research Institute, Faculty of Dentistry, University of Otago  Dunedin New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Monica","family":"Tromp","sequence":"additional","affiliation":[{"name":"Department of Anatomy University of Otago  Dunedin New Zealand"},{"name":"Southern Pacific Archaeological Research, Archaeology Programme, School of Social Sciences, University of Otago  Dunedin New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hallie R.","family":"Buckley","sequence":"additional","affiliation":[{"name":"Department of Anatomy University of Otago  Dunedin New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,9,11]]},"reference":[{"issue":"1","key":"e_1_2_9_2_1","first-page":"1","article-title":"The histological paradox: Methodology and efficacy of dental sectioning","volume":"29","author":"Aris C.","year":"2020","journal-title":"Papers from the Institute of Archaeology"},{"issue":"3","key":"e_1_2_9_3_1","first-page":"95","article-title":"Using teeth as tools: Investigating the mother\u2013infant dyad and developmental origins of health and disease hypothesis using vitamin D deficiency","volume":"25","author":"Brickley M. 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