{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T05:40:15Z","timestamp":1792215615352,"version":"4.4.0"},"reference-count":39,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T00:00:00Z","timestamp":1792108800000},"content-version":"vor","delay-in-days":15,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["American Journal of Biological Anthropology"],"published-print":{"date-parts":[[2026,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    Interglobular dentin (IGD) has been used as a biomarker for vitamin D deficiency (VDD) in past populations. However, an evidence\u2010based threshold for the levels of serum vitamin D associated with IGD occurrence has not been established. Here, we explore the association between perinatal serum vitamin D levels, presence of IGD, and biological sex in the deciduous teeth of modern children from Otago, New Zealand. Ground sections were created from the deciduous central or lateral mandibular incisors of 54 five to 6\u2010year\u2010old children (27 M, 27 F) with known perinatal blood vitamin D levels. Vitamin D levels at birth were classified as deficient (\u2264\u200930\u2009nmol\/L), insufficient (&gt;\u200930mn\/L\u2013&lt;\u200950\u2009nmol\/L), or sufficient (\u2265\u200950\u2009nmol\/L), and scanned slides were scored blind by two observers for IGD presence or absence. Thirty\u2010seven individuals (68.5%) exhibited IGD. The distribution of IGD was similar across vitamin D levels considered deficient (35.1%), insufficient (32.4%), and sufficient (32.4%), with no significant association between IGD presence and vitamin D status (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.97) or IGD presence and sex (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.77). Our findings do not support an association between IGD formation in deciduous teeth and vitamin D levels at birth. The prevalence of IGD across the sample, particularly in secondary dentin, suggests IGD may represent a normal developmental feature. However, it is important to note that cord blood vitamin D levels do not reflect the individual's vitamin D status during the entire period of deciduous incisor formation. Further longitudinal clinical research is required to better understand the relationship between VDD and the formation of IGD.\n                  <\/jats:p>","DOI":"10.1002\/ajpa.70370","type":"journal-article","created":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T04:45:31Z","timestamp":1792212331000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Serum Vitamin D Levels at Birth Are Not Associated With the Formation of Interglobular Dentin in Deciduous Teeth of Modern New Zealand Children"],"prefix":"10.1002","volume":"191","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0516-785X","authenticated-orcid":false,"given":"Anne Marie","family":"Sohler\u2010Snoddy","sequence":"first","affiliation":[{"name":"Department of Biology University of North Carolina Greensboro  Greensboro North Carolina USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-1307-3916","authenticated-orcid":false,"given":"Stephanie","family":"Chan","sequence":"additional","affiliation":[{"name":"Sir John Walsh Research Institute, Faculty of Dentistry, University of Otago  Dunedin Otago New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rebecca","family":"Weastell","sequence":"additional","affiliation":[{"name":"Sir John Walsh Research Institute, Faculty of Dentistry, University of Otago  Dunedin Otago New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-0284-8346","authenticated-orcid":false,"given":"Victoria","family":"Chen","sequence":"additional","affiliation":[{"name":"Sir John Walsh Research Institute, Faculty of Dentistry, University of Otago  Dunedin Otago New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3348-5238","authenticated-orcid":false,"given":"Benjamin J.","family":"Wheeler","sequence":"additional","affiliation":[{"name":"Department of Paediatrics and Child Health University of Otago  Dunedin New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9726-9150","authenticated-orcid":false,"given":"Deanna","family":"Beckett","sequence":"additional","affiliation":[{"name":"Sir John Walsh Research Institute, Faculty of Dentistry, University of Otago  Dunedin Otago New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8949-4008","authenticated-orcid":false,"given":"Carolina","family":"Loch","sequence":"additional","affiliation":[{"name":"Sir John Walsh Research Institute, Faculty of Dentistry, University of Otago  Dunedin Otago New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,10,16]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/0030\u20104220(88)90165\u2010x"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/jbmr.4928"},{"key":"e_1_2_9_4_1","volume-title":"Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism","author":"Bickle D. 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A.","year":"2012"},{"issue":"1","key":"e_1_2_9_39_1","doi-asserted-by":"crossref","DOI":"10.3390\/nu10010086","article-title":"A Longitudinal Study of 25\u2010Hydroxy Vitamin D and Parathyroid Hormone Status Throughout Pregnancy and Exclusive Lactation in New Zealand Mothers and Their Infants at 450 South","volume":"10","author":"Wheeler B. J.","year":"2018","journal-title":"Nutrients"},{"issue":"4","key":"e_1_2_9_40_1","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1016\/j.archoralbio.2009.01.002","article-title":"Different Enamel and Dentin Mineralization Observed in VDR Deficient Mouse Model","volume":"54","author":"Zhang X.","year":"2009","journal-title":"Archives of Oral Biology"}],"container-title":["American Journal of Biological Anthropology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ajpa.70370","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/ajpa.70370","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ajpa.70370","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T04:45:54Z","timestamp":1792212354000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ajpa.70370"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,10]]},"references-count":39,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2026,10]]}},"alternative-id":["10.1002\/ajpa.70370"],"URL":"https:\/\/doi.org\/10.1002\/ajpa.70370","archive":["Portico"],"relation":{},"ISSN":["2692-7691","2692-7691"],"issn-type":[{"value":"2692-7691","type":"print"},{"value":"2692-7691","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,10]]},"assertion":[{"value":"2026-06-19","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-10-05","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-10-16","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70370"}}