{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,18]],"date-time":"2026-04-18T23:10:47Z","timestamp":1776553847702,"version":"3.51.2"},"reference-count":26,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2022,8,3]],"date-time":"2022-08-03T00:00:00Z","timestamp":1659484800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Australas J Ultrason Med"],"published-print":{"date-parts":[[2022,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Non\u2010tubal ectopic pregnancy (NTEP) is a rare but significant early pregnancy complication which can result in maternal morbidity and mortality. There is however a lack of evidence\u2010based guidelines for the management of NTEP.<\/jats:p><\/jats:sec><jats:sec><jats:title>Purpose<\/jats:title><jats:p>To evaluate the success rates of expectant, medical and surgical management in the treatment of NTEP at our tertiary centre.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Retrospective cohort study from 2010 to 2020. All NTEP were classified by ectopic sites. Primary management was classified by expectant, medical [systemic methotrexate (Sys\u2010MTX) and\/or local ultrasound\u2010guided injection of MTX and\/or KCl intra\u2010sac (L\u2010MTX, L\u2010MTX\/KCl)] or surgical. Primary management was considered successful if no change in intervention was required. Treatment complications were compared.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Twenty\u2010four NTEP were identified, which included 14 interstitial pregnancies (IP), 9 caesarean scar pregnancies (CSP) and 1 ovarian pregnancy (OP), which gave NTEP an incidence of 7.12% among all EP (4.15% for IP, 2.67% for CSP and 0.30% for OP). The success of primary surgical management was 100% (7\/7), primary medical management was 76.9% (10\/13) and primary expectant management was 33.3% (1\/3). Primary medical management had a non\u2010statistically significant greater mean time to serum \u00df\u2010human Chorionic Gonadotrophin &lt;5\u2009IU\/L, mean length of hospitalisation, mean number of follow\u2010up visits and hospital re\u2010presentation\/readmissions compared to primary surgical management. There was no other difference in complication rates between the treatment management groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Surgery remains the most effective way to manage NTEP. However, medical management can be a safe and effective alternative option in carefully selected cases.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ajum.12312","type":"journal-article","created":{"date-parts":[[2022,8,3]],"date-time":"2022-08-03T16:59:28Z","timestamp":1659545968000},"page":"166-175","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["A 10\u2010year retrospective cohort study of non\u2010tubal ectopic pregnancy management outcomes in an Australian tertiary centre"],"prefix":"10.1002","volume":"25","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2301-1656","authenticated-orcid":false,"given":"Wei\u2010Guo Nicholas","family":"Loh","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynaecology Liverpool Hospital  Sydney New South Wales Australia"},{"name":"South Western Sydney Clinical School University of New South Wales  Sydney New South Wales 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